SYSTEMATIC REVIEW


Osseointegration of Hafnium when Compared to Titanium - A Structured Review



Vaishnavi Rajaraman1, *, Deepak Nallaswamy2, Dhanraj M. Ganapathy3, Saloni Kachhara3
1 Department of Prosthodontics, Saveetha University, Chennai- 600077, India
2 Saveetha Dental College and Hospital, Saveetha Institute Of Medical and Technical Sciences, Saveetha University, Chennai, India
3 Department of Prosthodontics and Implantology, Saveetha Dental College and Hospital, Saveetha Institute Of Medical and Technical Sciences, Saveetha University, Chennai, India


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Creative Commons License
© 2021 Rajaraman et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Department of Prosthodontics, Saveetha Dental College and Hospital, Saveetha Institute Of Medical and Technical Sciences, Saveetha University, Chennai, India; Tel: +8779565950; E-mail: drvaish.sav@gmail.com


Abstract

Aim:

This systematic review was conducted to analyse osseointegration of hafnium over conventional titanium.

Materials and Methods:

Search methodology was comprehended using PICO analysis and a comprehensive search was initiated in PubMed Central, Medline, Cochrane, Ovid, Science Direct, Copernicus and Google Scholar databases to identify the related literature. Randomised control trials, clinical studies, case control studies and animal studies were searched for osseointegration of hafnium coated titanium implants versus conventional titanium implants. Timeline was set to include all the manuscripts published till December 2018 in this review.

Clinical Significance:

Hafnium is a very promising surface coating intervention that can augment osseointegration in titanium implants. If research could be widened, including in vivo studies on hafnium as a metal for coating over dental implants or as a dental implant material itself to enhance better osseointegration, it could explore possibilities of this metal in the rehabilitation of both intra and extra oral defects and in medically compromised patients with poor quality of bone.

Results:

Out of the 25 articles obtained from the PICO based keyword search, 5 studies were excluded based on title and abstract. Out of the remaining 20 studies, 16 were excluded based on the inclusion and exclusion criteria of our interest and finally, 4 were included on the basis of core data.

Conclusion:

This systematic review observed hafnium metal exhibited superior osseointegration than titanium. Owing to its biocompatibility, hafnium could be an alternative to titanium, in the near future.

Keywords: Osseointegration, Hafnium, Conventional titanium, Bone implant contact, Titanium alloys, Tantalum.