Oral Aspects Identified in Atopic Dermatitis Patients: A Literature Review

Aline Domingues Tavares Oliveira5, Camila Stofella Sodré4, Dennis de Carvalho Ferreira3, 5, Eliane de Dios Abad6, Simone Saintive5, Márcia Ribeiro7, Fernanda Sampaio Cavalcante1, Bruna Piciani2, Lucio Souza Gonçalves3, *
1 Department of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
2 Department of Pathology, Fluminense Federal University, Rio de Janeiro, Brazil
3 Faculty of Dentistry, Estácio de Sá University, Rio de Janeiro, Brazil
4 Department of Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
5 Faculty of Dentistry, Veiga de Almeida University, Rio de Janeiro, Brazil
6 Pediatric Dermatology Service, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
7 Medical Genetics Service, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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© 2018 Oliveira et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to the author at the Faculty of Dentistry, Estácio de Sá University, Av. Alfredo Baltazar da Silveira, 580/cobertura, CEP: 22790-010 - Recreio - Rio de Janeiro/RJ - Brazil; Tel: 55 21 994550040; E-mail:



Atopic dermatitis is a chronic inflammatory skin condition that is more prevalent in children (10-20% of the world's population) than in adults. As its etiology is multifactorial, it is important to know the most frequent oral manifestations in atopic dermatitis patients.


In the last decades, the correlation between atopic dermatitis and conditions and/or changes in the oral cavity has been demonstrated by several studies. The objective of this paper was to describe, through a review of the literature, the oral health conditions and/or oral aspects identified in patients with atopic dermatitis.

Search Strategy:

A descriptive literature review was carried out through a bibliographical survey based on the last 10 years, in order to answer the study questions.


As a result, we found six studies with different sample sizes, ranging from 43 to 468 patients, and the majority of them were of cross-sectional study design.


Two studies performed their analysis through dental exams and reported that patients with atopic dermatitis tend to have a greater frequency of carious lesions, and two studies correlated Candida with atopic dermatitis through mycological analyzes.


There are a few studies in the literature that identify the oral aspects of atopic dermatitis. More investigations are needed in order to contribute to the knowledge of such oral aspects and the approach to treat these patients regarding oral health.

Keywords: Atopic dermatitis, Oral manifestations, Dental caries, Xeroderma, Nasopharyngeal mucosa, Chronic inflammatory skin condition.