Epithelial-Myoepithelial Carcinoma of High Grade Transformation: The Case Report in the Buccal Mucosa

Francisco Jadson Lima 1, *, Damião Edgleys Porto 2, Josuel Raimundo Cavalcante 1, Salomão Cury-Rad Oka 1, Gustavo Pina Godoy 1
1 Dentistry Postgraduate Program, State University of Paraíba, Brazil
2 Oral and Maxillofacial Surgeon, Pivate Practice, Brazil

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© Lima et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Dentistry Postgraduate Program, State University of Paraíba, Brazil Rua Juvêncio Arruda, S/N - Bodocongó Departamento de Odontologia - Campus Bodocongó CEP: 58.429-600; Tel: 55 (83) 3315-3471; Fax: 55 (83) 9626 – 7573; Emails:,


Epithelial-myoepithelial carcinoma was first described by Danath et al. in 1972 and is classified as a rare low-grade biphasic neoplasm of the salivary glands. This case report presents a male patient who had a lesion in the oral mucosa with a history of recurrence of the tumor. The outcome resulted in a profile consistent with an epithelial-myoepithelial carcinoma with a high degree of transformation. The case highlights the importance of histopathological evaluation of oral lesions, which occasionally may not present typical clinical aspects of malignant lesion.

Keywords: Dentistry, Diagnosis, Oral Cancer, Oral Diagnosis, Pathology, Salivary Glands.