Oral Inflammatory Myofibroblastic Tumor: Case Report and Review of Literature
Nada O Binmadi a, *, Harold Packman b, John C Papadimitriou c, Mark Scheper a
Identifiers and Pagination:Year: 2011
First Page: 66
Last Page: 70
Publisher Id: TODENTJ-5-66
Article History:Received Date: 1/12/2010
Revision Received Date: 21/1/2011
Acceptance Date: 24/1/2011
Electronic publication date: 13/4/2011
Collection year: 2011
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Inflammatory myofibroblastic tumor (IMT) is a rarely described tumor of unknown etiology and pathogenesis. It occurs primarily in the lungs, but has occurred in other extra-pulmonary sites. Histologically these lesions appear as an inflammatory infiltrate within a variably myofibrotic background. Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK kinase, which is often assessed using immunohistochemical studies. Currently, the biological behavior of oral inflammatory myofibroblastic tumor is still uncertain. This article describes the clinical, histological, and operative features of a case of IMT of the oral cavity.