Oral Manifestations in Pediatric Patients with Coeliac Disease – A Review Article

Viviana Marisa Pereira Macho1, *, Ana Sofia Coelho2, Diana Maria Veloso e Silva3, David José Casimiro de Andrade4
1 Pediatric Dentistry, Faculty of Dentistry, University of Porto, Porto, Portugal
2 Faculty of Medicine, University of Coimbra, Coimbra, Portugal
3 Clinical Nutrition, Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal
4 Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University, of Porto, Porto, Portugal

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© 2017 Macho et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Pediatric Dentistry, Faculty of Dentistry, University of Porto, Rua 31 de Janeiro nº22 1ºandar, 4900-533 Póvoa de Varzim - Portugal; Tel: +351966537296; E-mail: vivimacho@gmail.com



Coeliac disease is a chronic enteropathy that remains a challenge for the clinician, due to its atypical manifestations and etiopathogenic complexity.


This article intends to describe the oral characteristics of Coeliac Disease in children in order to facilitate their management in the dental office.


A review of the literature was performed electronically in PubMed (PubMed Central, and MEDLINE) for articles published in English from 2000 to April of 2017. The article is also based on the authors' clinical experience with children with coeliac disease. The searched keywords were “coeliac disease “,”oral manifestations “, “dental enamel defects”, “recurrent aphthous stomatitis” and “oral aphthous ulcers”.


There are some oral manifestations which are strictly related to coeliac disease: dental enamel defects, recurrent aphthous stomatitis, delayed tooth eruption, multiple caries, angular cheilitis, atrophic glossitis, dry mouth and burning tongue.


The complete knowledge of the oral manifestations of coeliac disease can trigger an effective change in the quality of life of the patients with this disease.

Keywords: Coeliac disease, Oral manifestations, Dental enamel defects, Recurrent aphthous stomatitis, Oral aphthous ulcers, Gluten.