Platelet Rich Fibrin in Periodontal Regeneration



Muthukumaraswamy Arunachalam1, Shaju J. Pulikkotil2, *, Nath Sonia3
1 Department of Periodontology and Oral Implantology, Tamilnadu Government Dental College, Chennai, India
2 Department of Restorative Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
3 Department of Periodontology and Oral Implantology, Vananchal Dental College, Jharkhand, India


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© Arunachalam et al. ; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Restorative Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia; Pin 600 003; E-mail: drmkswamy@gmail.com


Abstract

Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can ‘jump start’ the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.

Keywords: Alveolar bone, Chronic bacterial infection, Periodontal regeneration, Platelet concentrate.