RESEARCH ARTICLE


Peripheral Desmoplastic Ameloblastoma in Adolescent Age: Clinico-Pathological and Immunohistochemical Analisys of a Case



Giacomo Oteri 1, Maria Lentini 2, Michele Pisano 1, Marco Cicciù 2, *
1 Department of Biomedical Sciences and Specialist Medical-Surgical Dentistry
2 Department of Human Pathology, University of Messina, Italy


Article Metrics

CrossRef Citations:
0
Total Statistics:

Full-Text HTML Views: 2668
Abstract HTML Views: 1305
PDF Downloads: 354
Total Views/Downloads: 4327
Unique Statistics:

Full-Text HTML Views: 1150
Abstract HTML Views: 814
PDF Downloads: 228
Total Views/Downloads: 2192



Creative Commons License
© Oteri et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Oral Surgery Medical Practitioner, Assistant Professor, Researcher, Department of Human Pathology, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Me, Italy, Tel: +390902216911; E-mail: acromarco@yahoo.it


Abstract

The Extraosseous or Peripheral Ameloblastoma (PA) is a rare and benign odontogenic tumour, representing 1% to 5% of all ameloblastomas. It is usually localized in the soft oral tissues, without deep bone involvement. Its biological behaviour is specific, and several authors define PA as a non-infiltrating hamartomatous lesion. Indeed, recurrences rarely occur and progression in malignant tumors appears to be rare.

The PA originates from the tooth-forming apparatus and it consists of proliferating odontogenic epithelium, exhibiting the same histological cell types and patterns of the intraosseous counterpart or infiltrating ameloblastoma.

The peripheral desmoplastic ameloblastoma (PDA) can be classified as a newly recognized and very rare histological variant. To our knowledge, only a few cases of adult patients affected by PDA have been published.

The aim of this paper is to report a case of PDA affecting an adolescent patient. The clinical-pathological and immunohistological features are discussed in order to improve knowledge regarding a correct diagnosis and to differentiate PDA lesions from similar diseases.

Keywords: Immune-histochemistry, peripheral desmoplastic ameloblastoma.