Rare Bilateral Nasopalatine Duct Cysts: A Case Report

Marco Cicciù1, *, Giovanni Battista Grossi1, Andrea Borgonovo1, Giacomo Santoro1, Francesco Pallotti2, Carlo Maiorana1
1 University of Milan, Department of Oral Surgery, I.C.P. Dental School via della Commenda 10 Milan, Italy
2 University of Milan, Fondazione IRCCS, Ospedale Maggiore Policlinico Milan, Italy

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© Cicciù et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Resident of Department of Oral Surgery and Implantology, University of Milan, IRCSS, Via della Commenda 10 Milano, 20140 Italy; Tel: +390255032621; E-mail:


The nasopalatine duct cyst (NPDC) is the most common of the non-odontogenic cyst of the jaws. This cysts are usually central or unilateral with no prevalence of side occurrence. The NPDC is the most frequent developmental, nonodontogenic cyst of the jaws. This cyst originates from epithelial remnants from the nasopalatine duct. The cells could be activated spontaneously during life, or are eventually stimulated by the irritating action of various agents (infection, etc.). Generally, patients present without clinical signs and symptoms. Therefore, the tentative diagnosis "nasopalatine duct cyst" is often based on a coincidental radiological finding on a routine panoramic view or occlusal radiograph. The definite diagnosis should be based on clinical, radiological and above all histopathologic findings. The therapy of nasopalatine duct cysts consists of an enucleation of the cystic tissue, only in rare cases a marsupialization needs to be performed. This report describes the appearance and treatment of a rare case of bilateral nasopalatine duct cyst.