Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in the head and neck region, especially
among those of Chinese origin. NPC has multifactorial aetiologies including genetic susceptibility, consumption of
food with high salt content, and the Epsteinâ€“Barr virus. The primary tumour usually arises from the lateral walls of the
nasopharynx and is characterized by a rich sub-mucosal lymphatic structure, often leading to cervical lymph node metastasis.
Distant metastasis has been recognized to be a major cause of treatment failure in patients with nasopharyngeal carcinoma.
Bone, liver and lung are the most frequent sites of NPC metastases.
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