Successful Treatment of Cheilitis Glandularis Accompanied by Pseudomonas aeruginosa Infection: A Case Report

Cheilitis glandularis (CG) is a rare inflammatory disorder affecting the minor salivary glands. Nonetheless, the ideal management of CG remains elusive. Hence, this study aimed to broaden the understanding of the etiopathogenesis of CG and recommend bacterial culture and drug sensitivity tests for CG patients with suspected infection.

A 78-year-old female came to our hospital complaining of painful protrusion in her right lower labial mucosa for three weeks. Clinical examination revealed local enlargement with pyorrhea on the right lower labial mucosa. Histopathological examination indicated the features of CG. Bacterial culture and drug sensitivity test demonstrated Pseudomonas aeruginosa (P. aeruginosa) infection with several susceptible antibiotics. The patient was treated with surgical excision of the right lower labial mucosa combined with levofloxacin daily for two weeks. At the 4-week follow-up after excision, only a small amount of scar remained in the excision area. The patient had no symptoms in the oral mucosa.

CG may be accompanied by P. aeruginosa infection. Bacterial culture and drug sensitivity tests may contribute to identifying potential pathogens in CG patients and improving the efficacy of the treatment.