RESEARCH ARTICLE


Use of a Collagen Matrix as a Substitute for Free Mucosal Grafts in Pre-Prosthetic Surgery: 1 Year Results From a Clinical Prospective Study on 15 Patients



Carlo Maiorana1, *, Mario Beretta1, Luca Pivetti1, Enrico Stoffella1, Giovanni B. Grossi1, Alan S. Herford2
1 Oral Surgery and Implantology Dental Clinic, Fondazione IRCCS Policlinico Ca'Granda, Via Francesco Sforza, Milano, Italy
2 Department of Oral & Maxillofacial Surgery, Loma Linda University, California, USA


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© Maiorana et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Fondazione IRCCS Policlinico Ca'Granda, Via della Commenda 10, 20122 Milan, Italy; Tel: 00390255032303; Fax: 0039028051204; E-mail: carlo.maiorana@unimi.it


Abstract

Background:

The presence of keratinized tissue around dental implants is more than desirable either from a functional and aesthetic point of view, making soft tissue grafting a common practice in implant rehabilitation. Autogenous soft tissue grafting procedures are usually associated with high morbidity. Aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants.

Methods:

15 consecutive patients underwent a vestibuloplasty and grafting, both in the mandible and the maxilla, with a collagen matrix.

Results:

The primary endpoint was to evaluate the resorption of the graft along with the re-epithelization grafted area. The percentage of the resorption was 44,4%, with a mean gain in vestibular height of 3 mm. Secondary endpoints evaluated the clinical appearance, the hemostatic effect and the post-operative pain. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection were noted.

Conclusion:

This study showed that the used collagen matrix can find major interest in those patients who need a greater aesthetic outcome as the matrix has a perfect integration with the surrounding tissues. Furthermore it is strongly recommended for those patients who can bear little pain.

Clinical Significance:

Post-operative morbidity of autologous grafts is the biggest concern of this type of surgery. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery.

The present study showed the efficacy of a collagen matrix as this kind of substitute.

Keywords: Collagen matrix, Keratinized tissue, Mucosal grafts, Vestibuloplasty, Xenogeneic graft.