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Efficacy of Sticky Bone with Repeated Injectable Platelet-rich Fibrin Application in the Management of Periodontal Intrabony Defects: Randomized Controlled Clinical Trial
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Mostafa Mohamed Hosny2
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Hisham Mohamed Abozaid2
Ahmed Halim Hashem2
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Abdel-Latif Galal Borhamy2
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Abdel-Aziz Kamal Abo-ammo2
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Ibrahim Sabry El Sayed2
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Ahmed Mohamed Elshamy2
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Mahmoud Taha El-Destawy2
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Authors Info & Affiliations
Abstract
Background
This study aimed to compare and evaluate the clinical and radiographic outcomes of using a xenograft alone versus a sticky bone combined with repeated injections of injectable platelet-rich fibrin [I-PRF] for the treatment of intrabony defects [IBDs] in patients with stage III periodontitis. The investigation was conducted with a rigorous randomized prospective study design, ensuring the validity of the results.
Methods
This clinical and radiographic study included thirty patients with intrabony defects [IBDs]. The defects were randomly assigned to one of two groups: Group I received xenograft alone, while Group II received a combination of injectable platelet-rich fibrin [I-PRF] and xenograft, along with repeated I-PRF injections. Clinical and radiographic assessments were performed at baseline, 6 months, and 9 months. The collected data were tabulated and analyzed using SPSS software, version 22.
Results
The test group, which received repeated injections of I-PRF with sticky bone, showed statistically significant improvements in IBD reduction at the individual site after six and nine months compared to the same periods in the control group.
Conclusion
This finding suggests that repeated injection of I-PRF with sticky bone may offer a more effective treatment option for managing IBDs than xenografts alone.