Clinical and Microbiological Effects of Systemic, Local, and Combined Application of Doxycycline in the Treatment of Periodontitis

Al-Shrabe, Abdolrhman Said; Al-Hajj, Wadhah Abdulnasser; Al-Hajri, Manal Mohammed; Alahmari, Manea Musa M.; Alahmari, Danah Manea M.; Al Moaleem, Mohammed M.; Homeida, Husham E; Mehta, Vini

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RESEARCH ARTICLE

Clinical and Microbiological Effects of Systemic, Local, and Combined Application of Doxycycline in the Treatment of Periodontitis

Abdolrhman Said Al-Shrabe¹ Wadhah Abdulnasser Al-Hajj² Manal Mohammed Al-Hajri³ Manea Musa M. Alahmari⁴ Danah Manea M. Alahmari⁵ Mohammed M. Al Moaleem⁶^{, *} Husham E Homeida⁷ Vini Mehta⁸ Authors Info & Affiliations

The Open Dentistry Journal • 25 June 2025 • RESEARCH ARTICLE • DOI: 10.2174/0118742106388003250619103615

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Abdolrhman Said Al-Shrabe ¹

Wadhah Abdulnasser Al-Hajj ²

Manal Mohammed Al-Hajri ³

Manea Musa M. Alahmari ⁴

Danah Manea M. Alahmari ⁵

Mohammed M. Al Moaleem ⁶^{, *}

Husham E Homeida ⁷

Vini Mehta ⁸

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The Open Dentistry Journal

RESEARCH ARTICLE

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Year: 2025

Volume: 19

E-location ID: e18742106388003

DOI: 10.2174/0118742106388003250619103615

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Al-Shrabe A, Al-Hajj W, Al-Hajri M, Alahmari M, Alahmari D, Al Moaleem M, Homeida H, Mehta V. Clinical and Microbiological Effects of Systemic, Local, and Combined Application of Doxycycline in the Treatment of Periodontitis . Open Dent J, 2025; 19: e18742106388003. http://dx.doi.org/10.2174/0118742106388003250619103615

Article History

Received Date: 23 Jan 2025

Revision Received Date: 10 May 2025

Electronic Publication Date: 25 June 2025

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open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Al-Shrabe A, Al-Hajj W, Al-Hajri M, Alahmari M, Alahmari D, Al Moaleem M, Homeida H, Mehta V. Clinical and Microbiological Effects of Systemic, Local, and Combined Application of Doxycycline in the Treatment of Periodontitis . Open Dent J, 2025; 19: e18742106388003. http://dx.doi.org/10.2174/0118742106388003250619103615

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Open-Access License: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Address correspondence to this author at the Department of Prosthetic Dental Science, College of Dentistry, Jazan University, 45142, Jazan, Saudi Arabia; E-mail: malmoaleem@jazanu.edu.sa

Clinical and Microbiological Effects of Systemic, Local, and Combined Application of Doxycycline in the Treatment of Periodontitis

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