Efficacy of Three Mouthwashes on Candida albicans in Patients with Denture Stomatitis: In Vivo Study

The oral mucosa provides an optimal environment for the colonization of microorganisms and fungi, exhibiting a variety of biological habitats. The accumulation of biofilm on dentures significantly contributes to the development of denture stomatitis. Mouthwashes have been proven to exhibit an antiseptic effect and are widely used due to their antimicrobial effects. This research aims to examine the antibacterial efficacy of three types of mouthwashes as denture cleansers for people with denture stomatitis.

Sixty patients were chosen from removable prosthodontics clinics and were categorized into groups treated with three different types of commercial mouthwashes (Tantum Verde, Hextol mouthwash, and Orovex). Subsequently, swabs were collected from each patient, and the fungal growth of Candida albicans was evaluated.

All studied mouthwashes (Tantum Verde, Hextol mouthwash, and Orovex) effectively decreased the quantity of bacteria on dentures. Mouthwashes containing chlorhexidine showed better results on the inhibition of the growth of C. albicans in comparison to other mouthwashes.

Maintaining proper oral hygiene for dentures is crucial for preventing and treating denture stomatitis. Chemical disinfectants are recognized for their significance over mechanical cleaning, such as effective disinfection and simplicity. Mouthwashes serve as an efficient method for cleaning dentures, and prolonged use may impact the material characteristics of the dentures, including surface roughness and coloration.

Tantum Verde, Hextol, and Orovex mouthwashes are effective in decreasing the C. albicans on dentures. The chlorhexidine mouthwashes show better results than other mouthwashes. Furthermore, using a wider array of microorganisms in future investigations might provide a more thorough comprehension of their involvement in denture-related complications.