A Lipoma of Large Proportion in the Oral Cavity: A Case Report

Lipoma is a benign neoplasm that can affect the whole body and rarely occurs in the oral cavity. It is slow-growing and asymptomatic, and conservative surgical treatment with total removal of the lesion is the treatment of choice. It originates from epithelial cells of mature adipose tissue.

The aim of this study was to report a clinical case of a large lipoma in a 21-year-old male patient with melanoderma who presented a nodule in the region of the buccal vestibule extending from the region of the second molar to the ipsilateral canine, with an approximate size of 40 mm in its largest diameter in the anteroposterior direction and approximately 20 mm in diameter in the buccolingual direction. The initial diagnostic hypothesis was based on an ultrasound of the face, which detected a solid, circumscribed, echogenic nodule compatible with a lipoma of the face. Surgical treatment with excisional biopsy was chosen. The histopathological examination revealed fragments with the presence of discrete acanthosis and clear hyperkeratosis in the epithelium, along with the proliferation of mature adipocytes constituting a neoplastic parenchyma surrounded by a stroma.

The findings have confirmed the diagnosis of oral lipoma. The patient has evolved with a good prognosis and remained under follow-up without recurrence or sequelae. The present report has corroborated what has been observed in similar cases described in the literature regarding recurrence and excellent prognosis.