Diagnosis and Intralesional Corticotherapy in Oral Ulcers Occurring as the Sole Manifestation of Langerhans Cell Histiocytosis. A Case Report
Liane Gambirazi, Tatiana Libório, Fábio Nunes, Norberto Sugaya, Dante Migliari*
Identifiers and Pagination:Year: 2016
First Page: 330
Last Page: 337
Publisher ID: TODENTJ-10-330
Article History:Received Date: 31/12/2015
Revision Received Date: 04/05/2016
Acceptance Date: 09/05/2016
Electronic publication date: 25/06/2016
Collection year: 2016
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This article reports a case of oral mucosa lesions as the sole manifestation in Langerhans cell histiocytosis (LCH). This is a very uncommon manifestation of LCH since this disease preferably affects the bones with frequent involvement of the jaws. LCH may also involve other organs, particularly the lungs, liver, lymph nodes, and skin. The highlights of this report are the differential diagnosis, immunohistochemical analysis and, mostly, the therapeutic approach.