TODENTJ-25-03-2019_TODENTJ-9-150 1553505660 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 5 15 2015 9 1 Caio V.G Roman-Torres José S Neto Marcio A Souza Humberto O Schwartz-Filho William C Brandt Ricardo E.A.S Diniz aim of this study was to evaluate the efficacy of periodontal scaling and oral hygiene instruction for patients with mild chronic periodontitis and rheumatoid arthritis through clinical periodontal parameters and laboratory tests for CRP (C- reactive protein) and ESR (erythrocyte sedimentation rate). Twelve individuals with rheumatoid arthritis and 12 healthy individuals were evaluated, with a mean age of 45.38 and 46.75 respectively, all female and with mild, chronic periodontitis. The participants were evaluated clinically and periapical radiographs were taken (T1), after which periodontal treatment was instituted. After ninety days (T2), new clinical and laboratory data were obtained. Probing depth, bleeding index, and plaque indexes were observed in both groups, and the results demonstrated reductions but no statistical differences. Laboratory tests for CRP and ESR produced higher values for the rheumatoid arthritis group with T1- T2 reductions on the average, but the values were still higher than in the health group. We conclude that periodontal therapy in patients with rheumatoid arthritis and mild chronic periodontitis showed a improvement in the periodontal clinical parameters and laboratory tests that were evaluated. 5 15 2015 150 153 TODENTJ-9-150 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2015-3-9 2015-4-1 2015-4-13 2015-5-15 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210601509010150 1553505660 https://opendentistryjournal.com/VOLUME/9/PAGE/150/ https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-150/TODENTJ-9-150.xml Trials Monsarrat P 14 253 2013 Monsarrat P, Vergnes JN, Cantagrel A , et al. Effect of periodontal treatment on the clinical parameters of patients with rheumatoid arthritis study protocol of the randomized, controlled ESPERA trial Trials 2013; 14 : 253. Rev Bras Reumatol Mota LM 53 141 2013 Mota LM, Cruz BA, Brenol CV , et al. Guidelines for the diagnosis of rheumatoid arthritis Rev Bras Reumatol 2013; 53 (2) : 141-57. Curr Opin Rheumatol Bingham CO III 25 345 2013 Bingham CO III, Moni M. Disclosures.periodontal disease and rheumatoid arthritis. the evidence accumulates for complex pathobiologic interactions Curr Opin Rheumatol 2013; 25 (3) : 345-53. J Clin Periodontol Reichert S 40 591 2013 Reichert S, Haffner M, Keyber G , et al. Detection of oral bacterial DNA in synovial fluid J Clin Periodontol 2013; 40 (6) : 591-8. Bras Patol Med Lab Goeldner I 47 495 2011 Goeldner I, Skare Tl, Reason ITM, Utiyama SRR. Artrite reumatoide uma visão atual Bras Patol Med Lab 2011; 47 (1) : 495-503. Med Hypotheses Liao F 72 732 2009 Liao F, Li Z, Wang Y, Shi B, Gong Z, Cheng X. Porphyromonas gingivalis may play an important role in the pathogenesis of periodontitis- associated rheumatoid arthritis Med Hypotheses 2009; 72 (6) : 732-5. Braz Oral Res Ishi EP 22 72 2008 Ishi EP, Bertolo MB, Rossa C Jr, Kirkwood Kl, Onofre MA. Periodontal condition in patients with rheumatoid arthritis Braz Oral Res 2008; 22 (1) : 72-. J Periodontol Dissik A 81 223 2010 Dissik A, Redman RS, Jones M , et al. Association of periodontitis with rheumatoid arthritis a pilot study J Periodontol 2010; 81 (2) : 223-30. Oral Dis Erciyas K 19 394 2013 Erciyas K, Sezer U, Ustün K , et al. Effects of periodontal therapy on disease activity and systemic inflammation in rheumatoid arthritis patients Oral Dis 2013; 19 (4) : 394-400. Ann Periodontol Armitage GC 4 1 1999 Armitage GC. Development of a classification system for periodontal diseases and conditions Ann Periodontol 1999; 4 (1) : 1-6. Arthritis Rheum Block SR 46 3102 2002 Block SR. Hidden hazards and practical problems comment on the 2002, update of the American College of Rheumatology Guidelines for the Management of Rheumatoid Arthritis Arthritis Rheum 2002; 46 (11) : 3102-. Int Dent J Ainamo J 25 229 1975 Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque Int Dent J 1975; 25 (4) : 229-35. J Periodontol Chan YK 71 385 2000 Chan YK, Needleman IG, Clifford LR. Comparison of four methods of assessing root surface debridement J Periodontol 2000; 71 (3) : 385-93. Recent Pat Endocr Metab Immune Drug Discov El-Shinnawi U 7 169 2013 El-Shinnawi U, Soory M. Associations between periodontitis and systemic inflammatory diseases response to treatment Recent Pat Endocr Metab Immune Drug Discov 2013; 7 (3) : 169-88. J Oral Microbiol Persson GR 4 2012 Persson GR. Rheumatoid arthritis and periodontitis – inflammatory and infectious connections.Review of the literature J Oral Microbiol 2012; 4 J Clin Periodontol Mercado F 27 267 2000 Mercado F, Marshall RI, Klestov AC, Bartold PM. Is there a relationship between rheumatoid arthritis and periodontal diseaseκ J Clin Periodontol 2000; 27 (4) : 267-72. J Periodontol Mayer Y 80 1414 2009 Mayer Y, Balbir-Gurman A, Machtei EE. Anti-tumor necrosis factor-alpha therapy and periodontal parameters in patients with rheumatoid arthritis J Periodontol 2009; 80 (9) : 1414-20. Joint Bone Spine Berthelot JM 77 537 2010 Berthelot JM, Le Goff B. Rheumatoid arthritis and periodontal disease Joint Bone Spine 2010; 77 (6) : 537-41. J Periodontal Implant Sci Han JY 42 3 2012 Han JY, Reynolds MA. Effect of antirheumatic agents on periodontal parametersand biomarkers of inflammation a systematic review and meta-analysis J Periodontal Implant Sci 2012; 42 (1) : 3-12. Rheumatol Int Joseph R 33 103 2013 Joseph R, Rajappan S, Nath SG, Paul BJ. Association between chronic periodontitis and rheumatoid arthritis a hospital-based case-control study Rheumatol Int 2013; 33 (1) : 103-9. J Periodontal Implant Sci Torkzaban P 42 67 2012 Torkzaban P, Hjiabadi T, Basiri Z, Poorolajal J. Effect of rheumatoid arthritis on periodontitis a historical cohort study J Periodontal Implant Sci 2012; 42 (3) : 67-72. Arthritis Rheum Aletha D 62 2569 2010 Aletha D, Neogi T, Silman AJ , et al. Rheumatoid arthritis classification criteria Arthritis Rheum 2010; 62 (9) : 2569-81. Rev Assoc Med Bras Aguiar FJB 59 85 2013 Aguiar FJB, Ferreira-Júnior M, Sales MM , et al. Proteína C reativa aplicações clínicas e propostas para utilização racional Rev Assoc Med Bras 2013; 59 (1) : 85-92.