TODENTJ-25-03-2019_TODENTJ-9-146 1553505658 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 3 31 2015 9 1 Shigeru Maeda Yumiko Tomayasu Hitoshi Higuchi Minako Ishii-Maruhama Ayaka Yamane Akiko Yabuki Yuka Honda Masahiko Egusa Takuya Miyawaki Purpose : The purpose of this study was to identify independent factors associated with prolonged recovery time after intravenous sedation for dental treatment in patients with intellectual disabilities. Methods : This study was designed as a prospective cohort study. Participants were patients with intellectual disabilities, for whom sedation for dental treatment was planned in Okayama University Hospital. The outcome variable was recovery time. The predictor variables were patient background, antiepileptic and psychotropic drugs, and anesthesia-related variables. Factors affecting the outcome were examined with multiple regression analysis. Results : We enrolled 260 cases in this study. Oral midazolam was a strong independent determinant in prolonged recovery time. Teeth extraction, short treatment time and lower body mass index were significant independent predictors of prolonged recovery time. Conclusion : Oral midazolam is a clear independent determinant of prolonged recovery time after sedation, while psychotropic drugs and antiepileptic drugs were not independent determinants in this study. 3 31 2015 146 149 TODENTJ-9-146 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2015-1-2 2015-3-18 2015-3-20 2015-3-31 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210601509010146 1553505658 https://opendentistryjournal.com/VOLUME/9/PAGE/146/ https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.pdf https://opendentistryjournal.com/contents/volumes/V9/TODENTJ-9-146/TODENTJ-9-146.xml J Clin Anesth. 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