TODENTJ-25-03-2019_TODENTJ-8-194 1553505570 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 11 14 2014 8 1 Alessandro Cucchi Paolo Ghensi Guided bone regeneration (GBR) standard protocols call for filling the space underneath the membrane with autogenous bone or a mixture composed of autogenous bone particles and allogeneic bone tissue or heterologous biomaterials. This work describes the case of a GBR performed to restore a vertical bone defect with simultaneous placement of a dental implant in the posterior mandible that was carried out using a high density d-PTFE membrane and corticocancellous porcine-derived bone without the addition of any autogenous bone. Bone regeneration was assessed by histological analysis of a biopsy sample collected from the grafted site nine months after the surgery. Intraoral radiographs taken at follow-up visits showed complete maintenance of the peri-implant bone levels for up to two years after prosthesis delivery. The regenerated site successfully supported functional loading of the implant. The present case report suggests that the use of a heterologous bone substitute alone to restore a vertical defect in a GBR procedure can be as effective as the standard protocol, while avoiding the drawbacks associated with a second surgical site opening. 11 14 2014 194 200 TODENTJ-8-194 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2014-5-21 2014-8-2 2014-9-9 2014-11-14 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210601408010194 1553505570 https://opendentistryjournal.com/VOLUME/8/PAGE/194/ https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.pdf https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-194/TODENTJ-8-194.xml J Prosthet Dent. 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