<?xml version="1.0"?>
<doi_batch xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.crossref.org/schema/4.4.0" xmlns:fr="http://www.crossref.org/fundref.xsd" xmlns:ct="http://www.crossref.org/clinicaltrials.xsd" xmlns:ai="http://www.crossref.org/AccessIndicators.xsd" xmlns:rel="http://www.crossref.org/relations.xsd" xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1" version="4.4.0" xsi:schemaLocation="http://www.crossref.org/schema/4.4.0 crossref4.4.0.xsd">
  <head>
    <doi_batch_id>TODENTJ-25-03-2019_TODENTJ-8-125</doi_batch_id>
    <timestamp>1553505540</timestamp>
    <depositor>
      <depositor_name>Bentham Open</depositor_name>
      <email_address>doi@benthamopen.net</email_address>
    </depositor>
    <registrant>Bentham Open</registrant>
  </head>
  <body>
    <journal>
      <journal_metadata language="en">
        <full_title>The Open Dentistry Journal</full_title>
        <abbrev_title>TODENTJ</abbrev_title>
        <issn media_type="print">1874-2106</issn>
      </journal_metadata>
      <journal_issue>
        <publication_date media_type="print">
          <month>6</month>
          <day>13
                </day>
          <year>2014</year>
        </publication_date>
        <journal_volume>
          <volume>8</volume>
        </journal_volume>
        <issue>1</issue>
      </journal_issue>
      <journal_article publication_type="full_text">
        <titles>
          <title>A Gray-purple Mass on the Floor of the Mouth: Gigantic Mucogingival Pyogenic Granuloma in a Teenage Patient</title>
        </titles>
        <contributors>
          <person_name contributor_role="author" sequence="first">
            <given_name>Lluís </given_name>
            <surname>Brunet-LLobet </surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Jaume </given_name>
            <surname>Miranda-Rius </surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Eduard </given_name>
            <surname>Lahor-Soler </surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Ombeni </given_name>
            <surname>Mrina </surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Alfons </given_name>
            <surname>Nadal </surname>
          </person_name>
        </contributors>
        <jats:abstract>
                <jats:p>Pyogenic granuloma is defined as a benign neoplasm of vascular phenotype. This case describes the clinical and histopathological features of a gigantic mucogingival pyogenic granuloma, in a 14-year-old healthy black boy. This exophytic gray-purple mass, related to a toothpick injury, had more than twelve-month evolution on the anterior mandible involving lingual area besides to the floor of the mouth pressing the right salivary duct. Conservative excision was performed, followed by uncomplicated healing with no recurrence in two years. The histopathological examination reported a pyogenic granuloma (lobular capillary haemangioma). The authors provide a discussion of the presurgical differential diagnosis of the lesion. This case report presents an extremely uncommon location of a gigantic pyogenic granuloma, involving mucogingival complex and affecting the salivary outflow. This clinical manuscript may shed light on the controversies about possible mechanisms inducing oral pyogenic granuloma.</jats:p>
            </jats:abstract>
        <publication_date>
          <month>6</month>
          <day>13
                </day>
          <year>2014</year>
        </publication_date>
        <pages>
          <first_page>125</first_page>
          <last_page>128</last_page>
        </pages>
        <publisher_item>
          <identifier id_type="sici">TODENTJ-8-125</identifier>
        </publisher_item>
        <crossmark>
          <crossmark_version>1</crossmark_version>
          <crossmark_policy>10.2174/crossmark_policy</crossmark_policy>
          <crossmark_domains>
            <crossmark_domain>
              <domain>opendentistryjournal.com</domain>
            </crossmark_domain>
            <crossmark_domain>
              <domain>benthamopen.com</domain>
            </crossmark_domain>
          </crossmark_domains>
          <crossmark_domain_exclusive>true</crossmark_domain_exclusive>
          <custom_metadata>
            <assertion name="review_status" label="Review Status" group_name="peer_review_details" group_label="Peer Review Details" order="0">Peer Reviewed</assertion>
            <assertion name="review_process" label="Review Process" group_name="peer_review_details" group_label="Peer Review Details" order="1">Single blind</assertion>
            <assertion name="screening_status" label="Screening Status" group_name="plagiarism_screening" group_label="Plagiarism Screening" order="0">Checked with iThenticate</assertion>
            <assertion name="received" label="Received" group_name="publication_history" group_label="Publication History" order="0">2014-2-27</assertion>
            <assertion name="revised" label="Revised" group_name="publication_history" group_label="Publication History" order="1">2014-3-15</assertion>
            <assertion name="accepted" label="Accepted" group_name="publication_history" group_label="Publication History" order="2">2014-3-18</assertion>
            <assertion name="published" label="Published" group_name="publication_history" group_label="Publication History" order="3">2014-6-13
                </assertion>
            <ai:program name="AccessIndicators">
              <ai:license_ref>http://creativecommons.org/licenses/by-nc/3.0/</ai:license_ref>
            </ai:program>
          </custom_metadata>
        </crossmark>
        <doi_data>
          <doi>10.2174/1874210601408010125</doi>
          <timestamp>1553505540</timestamp>
          <resource>https://opendentistryjournal.com/VOLUME/8/PAGE/125/</resource>
          <collection property="crawler-based">
            <item crawler="google">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item crawler="msn">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item crawler="altavista">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item crawler="yahoo">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item crawler="scirus">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item crawler="iParadigms">
              <resource>https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
          </collection>
          <collection property="text-mining">
            <item>
              <resource mime_type="application/pdf">https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.pdf</resource>
            </item>
            <item>
              <resource mime_type="application/xml">https://opendentistryjournal.com/contents/volumes/V8/TODENTJ-8-125/TODENTJ-8-125.xml</resource>
            </item>
          </collection>
        </doi_data>
        <citation_list>
          <citation key="refR1">
            <journal_title>J Oral Maxillofac Pathol</journal_title>
            <author>Kamal R</author>
            <volume>16</volume>
            <first_page>79</first_page>
            <cYear>2012</cYear>
            <unstructured_citation>
                    Kamal R, Dahiya P, Puri A. 
                    Oral pyogenic granuloma: various concepts of etiopathogenesis. 
                    J Oral Maxillofac Pathol  
                    2012; 
                    16
                    (1)
                    : 79-82.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR2">
            <journal_title>Int J Oral Sci</journal_title>
            <author>Miranda Rius J</author>
            <volume>5</volume>
            <first_page>172</first_page>
            <cYear>2013</cYear>
            <unstructured_citation>
                    Miranda Rius J, Nadal A, Lahor E, Mtui B, Brunet L. 
                    Unusual presentation of localized gingival enlargement associated with a slow-growing odontogenic myxoma. 
                    Int J Oral Sci  
                    2013; 
                    5
                    : 172-5.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR3">
            <journal_title>J Oral Sci</journal_title>
            <author>Jafarzadeh H</author>
            <volume>48</volume>
            <first_page>167</first_page>
            <cYear>2006</cYear>
            <unstructured_citation>
                    Jafarzadeh H, Sanatkhani M, Mohtasham N. 
                    Oral pyogenic granuloma: a review. 
                    J Oral Sci  
                    2006; 
                    48
                    (4)
                    : 167-75.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR4">
            <journal_title>Br J Oral Maxillofac Surg</journal_title>
            <author>Vilmann A</author>
            <volume>24</volume>
            <first_page>376</first_page>
            <cYear>1986</cYear>
            <unstructured_citation>
                    Vilmann A, Vilmann P, Vilmann H. 
                    Pyogenic granuloma: evaluation of oral conditions. 
                    Br J Oral Maxillofac Surg  
                    1986; 
                    24
                    (5)
                    : 376-82.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR5">
            <journal_title>Pediatr Dermatol</journal_title>
            <author>Pagliai KA</author>
            <volume>21</volume>
            <first_page>10</first_page>
            <cYear>2004</cYear>
            <unstructured_citation>
                    Pagliai KA, Cohen BA. 
                    Pyogenic granuloma in children. 
                    Pediatr Dermatol  
                    2004; 
                    21
                    (1)
                    : 10-3.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR6">
            <journal_title>J Periodontol</journal_title>
            <author>Yih WY</author>
            <volume>71</volume>
            <first_page>482</first_page>
            <cYear>2000</cYear>
            <unstructured_citation>
                    Yih WY, Richardson L, Kratochvil FJ , et al. 
                    Expression of estrogen receptors in desquamative gingivitis. 
                    J Periodontol  
                    2000; 
                    71
                    (3)
                    : 482-7.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR7">
            <journal_title>Br J Oral Maxillofac Surg</journal_title>
            <author>Saravana GH</author>
            <volume>47</volume>
            <first_page>318</first_page>
            <cYear>2009</cYear>
            <unstructured_citation>
                    Saravana GH. 
                    Oral pyogenic granuloma: a review of 137 cases. 
                    Br J Oral Maxillofac Surg  
                    2009; 
                    47
                    (4)
                    : 318-9.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR8">
            <journal_title>Open Dent J</journal_title>
            <author>Verma PK</author>
            <volume>6</volume>
            <first_page>153</first_page>
            <cYear>2012</cYear>
            <unstructured_citation>
                    Verma PK, Srivastava R, Baranwal H , et al. 
                    Pyogenic granuloma-hyperplastic lesion of the gingiva: case reports. 
                    Open Dent J  
                    2012; 
                    6
                    : 153-6.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR9">
            <journal_title>Int Dent Clin</journal_title>
            <author>Mathur LK</author>
            <volume>2</volume>
            <first_page>56</first_page>
            <cYear>2010</cYear>
            <unstructured_citation>
                    Mathur LK, Bhalodi AP, Manohar B , et al. 
                    Focal fibrous hyperplasia: a case report. 
                    Int Dent Clin  
                    2010; 
                    2
                    (4)
                    : 56-7.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR10">
            <journal_title> J Periodontol Res </journal_title>
            <author>Yuan K</author>
            <volume>35</volume>
            <first_page>165</first_page>
            <cYear>2000</cYear>
            <unstructured_citation>
                    Yuan K, Jin YT, Lin MT. 
                    Expression of Tie-2. angiopoietn-1.angiopoietin-2., ephrinB2 and ephrinB4 in pyogenic granuloma of human gingival implicates in their roles in inflammatory angiogenesis. 
                     J Periodontol Res   
                    2000; 
                    35
                    (3)
                    : 165-71.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR11">
            <journal_title>Ann Acad Med Singapore</journal_title>
            <author>Ong MA</author>
            <volume>27</volume>
            <first_page>258</first_page>
            <cYear>1998</cYear>
            <unstructured_citation>
                    Ong MA, Chai WL, Ngeow WC. 
                    Recurrent gigantic pyogenic granuloma disturbing speech and mastication: a case report and literature review. 
                    Ann Acad Med Singapore  
                    1998; 
                    27
                    : 258-61.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR12">
            <journal_title>Arch Pediatr Adolesc Med</journal_title>
            <author>Willies Jacobo LJ</author>
            <volume>154</volume>
            <first_page>603</first_page>
            <cYear>2000</cYear>
            <unstructured_citation>
                    Willies Jacobo LJ, Isaacs H Jr, Stein MT. 
                    Pyogenic granuloma presenting as a congenital epulis. 
                    Arch Pediatr Adolesc Med  
                    2000; 
                    154
                    (6)
                    : 603-5.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR13">
            <unstructured_citation>
                    Neville BW, Damm DD, Allen CM, Bouquot JE, Eds. 
                    Oral &amp; maxillofacial pathology. 
                     Philadelphia:  WB Saunders: 2002; pp. 
                    
                    
                    
                    437-95.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR14">
            <unstructured_citation>
                    Bouquot JE, Nikai H, Gnepp DR, Eds. 
                    Lesions of the oral cavity. 
                    In: Diagnostic surgical pathology of the head and neck 2001  .  
                    Philadelphia: WB Saunders: 2001; pp. 
                    
                    
                    141-233.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR15">
            <journal_title>Arch Otolaryngol</journal_title>
            <author>Fechner RE</author>
            <volume>107</volume>
            <first_page>30</first_page>
            <cYear>1981</cYear>
            <unstructured_citation>
                    Fechner RE, Cooper PH, Mills SE. 
                    Pyogenic granuloma of the larynx and trachea: a causal and pathologic misnomer for granulation tissue. 
                    Arch Otolaryngol  
                    1981; 
                    107
                    : 30-2.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR16">
            <journal_title>Oral Surg Oral Med Oral Pathol Oral Radiol Endod</journal_title>
            <author>Motamedi MH</author>
            <volume>103</volume>
            <first_page>e39</first_page>
            <cYear>2007</cYear>
            <unstructured_citation>
                    Motamedi MH, Eshghyar N, Jafari SM , et al. 
                    Peripheral and central giant cell granulomas of the jaws: a demographic study. 
                    Oral Surg Oral Med Oral Pathol Oral Radiol Endod  
                    2007; 
                    103
                    (6)
                    : e39-43.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR17">
            <journal_title>Ultraschall Med</journal_title>
            <author>Chen H</author>
            <volume>32 </volume>
            <first_page>S1</first_page>
            <cYear>2011</cYear>
            <unstructured_citation>
                    Chen H, Zhao Z, Gong X , et al. 
                    A tongue granuloma due to a fishbone mimicking a neoplasm: ultrasound-guided differential diagnosis. 
                    Ultraschall Med  
                    2011; 
                    32 
                    (Suppl 1
                )
                    : S1-2.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR18">
            <journal_title>Head Neck</journal_title>
            <author>Gouvêa AF</author>
            <volume>5</volume>
            <first_page>86</first_page>
            <cYear>2011</cYear>
            <unstructured_citation>
                    Gouvêa AF, Hanemann JA, Pereira AA , et al. 
                    Uncommon foreign body reactions occurring in the lip: clinical misdiagnosis and the use of special techniques of analysis. 
                    Head Neck  
                    2011; 
                    5
                    (1)
                    : 86-91.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR19">
            <journal_title>Oral Surg Oral Med Oral Pathol Oral Radiol</journal_title>
            <author>Fatahzadeh M</author>
            <volume>113</volume>
            <first_page>2</first_page>
            <cYear>2012</cYear>
            <unstructured_citation>
                    Fatahzadeh M. 
                    Kaposi sarcoma: review and medical management update. 
                    Oral Surg Oral Med Oral Pathol Oral Radiol  
                    2012; 
                    113
                    (1)
                    : 2-16.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR20">
            <journal_title>Pathol Int</journal_title>
            <author>Epivanatos A</author>
            <volume>55</volume>
            <first_page>391</first_page>
            <cYear>2005</cYear>
            <unstructured_citation>
                    Epivanatos A, Antoniades D, Zaraboukas T , et al. 
                    Pyogenic granuloma of the oral cavity: comparative study of its clinicopathological and immunohistochemical features. 
                    Pathol Int  
                    2005; 
                    55
                    (7)
                    : 391-7.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR21">
            <journal_title>Indian J Dent Res</journal_title>
            <author>Patil K</author>
            <volume>17</volume>
            <first_page>199</first_page>
            <cYear>2006</cYear>
            <unstructured_citation>
                    Patil K, Mahima VG, Lahari K. 
                    Extragingival pyogenic granuloma. 
                    Indian J Dent Res  
                    2006; 
                    17
                    (4)
                    : 199-202.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR22">
            <journal_title>J Dermatol</journal_title>
            <author>Ichimiya M</author>
            <volume>31</volume>
            <first_page>342</first_page>
            <cYear>2004</cYear>
            <unstructured_citation>
                    Ichimiya M, Yoshikawa Y, Hamamoto Y , et al. 
                    Successful treatment of Pyogenic granuloma with injection of absolute ethanol. 
                    J Dermatol  
                    2004; 
                    31
                    (4)
                    : 342-4.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR23">
            <journal_title>Arch Dermatol</journal_title>
            <author>Moon SE</author>
            <volume>141</volume>
            <first_page>644</first_page>
            <cYear>2005</cYear>
            <unstructured_citation>
                    Moon SE, Hwang EJ, Cho KH. 
                    Treatment of pyogenic granuloma by sodium tetradecyl sulphate sclerotherapy. 
                    Arch Dermatol  
                    2005; 
                    141
                    (5)
                    : 644-.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR24">
            <journal_title>Lasers Surg Med</journal_title>
            <author>Powell JL</author>
            <volume>14</volume>
            <first_page>178</first_page>
            <cYear>1994</cYear>
            <unstructured_citation>
                    Powell JL, Bailey CL, Coopland AT , et al. 
                    Nd: YAG laser excision of a giant gingival pyogenic granuloma of pregnancy. 
                    Lasers Surg Med  
                    1994; 
                    14
                    (2)
                    : 178-83.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR25">
            <journal_title>Dermatol Surg</journal_title>
            <author>Meffert JJ</author>
            <volume>24</volume>
            <first_page>845</first_page>
            <cYear>1998</cYear>
            <unstructured_citation>
                    Meffert JJ, Cagna DR, Meffert RM. 
                    Treatment of oral granulation tissue with the flashlamp pulsed dye laser. 
                    Dermatol Surg  
                    1998; 
                    24
                    (8)
                    : 845-.
                    
                </unstructured_citation>
          </citation>
          <citation key="refR26">
            <journal_title>Pathol Int</journal_title>
            <author>Toida M</author>
            <volume>53</volume>
            <first_page>1</first_page>
            <cYear>2003</cYear>
            <unstructured_citation>
                    Toida M, Hasegawa T, Watanabe F , et al. 
                    Lobular capillary hemangioma of the oral mucosa: clinicopathological study of 43 cases with a special reference to immunohistochemical characterization of the vascular elements. 
                    Pathol Int  
                    2003; 
                    53
                    (1)
                    : 1-7.
                    
                </unstructured_citation>
          </citation>
        </citation_list>
      </journal_article>
    </journal>
  </body>
</doi_batch>
