Dental Stem Cells and their Applications in Dental Tissue Engineering

TODENTJ-25-03-2019_TODENTJ-7-76 1553505463 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 7 26 2013 7 1 Dental Stem Cells and their Applications in Dental Tissue Engineering S Lymperi C Ligoudistianou V Taraslia E Kontakiotis E Anastasiadou Tooth loss or absence is a common condition that can be caused by various pathological circumstances. The replacement of the missing tooth is important for medical and aesthetic reasons. Recently, scientists focus on tooth tissue engineering, as a potential treatment, beyond the existing prosthetic methods. Tooth engineering is a promising new therapeutic approach that seeks to replace the missing tooth with a bioengineered one or to restore the damaged dental tissue. Its main tool is the stem cells that are seeded on the surface of biomaterials (scaffolds), in order to create a biocomplex. Several populations of mesenchymal stem cells are found in the tooth. These different cell types are categorized according to their location in the tooth and they demonstrate slightly different features. It appears that the dental stem cells isolated from the dental pulp and the periodontal ligament are the most powerful cells for tooth engineering. Additional research needs to be performed in order to address the problem of finding a suitable source of epithelial stem cells, which are important for the regeneration of the enamel. Nevertheless, the results of the existing studies are encouraging and strongly support the belief that tooth engineering can offer hope to people suffering from dental problems or tooth loss. 7 26 2013 76 81 TODENTJ-7-76 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2012-8-2 2013-1-29 2013-1-31 2013-7-26 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210601307010076 1553505463 https://opendentistryjournal.com/VOLUME/7/PAGE/76/ https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.pdf https://opendentistryjournal.com/contents/volumes/V7/TODENTJ-7-76/TODENTJ-7-76.xml Development Hall PA 106 619 1989 Hall PA, Watt FM. Stem cells the generation and maintenance of cellular diversity Development 1989; 106 (4) : 619-33. Cell Wagers AJ 16 639 2004 Wagers AJ, Weissman IL. Plasticity of adult stem cells Cell 2004; 16 (5) : 639-48. Cytotherapy Gimble J , 5 362 2003 Gimble J, Guilak F. Adipose-derived adult stem cells: isolation. characterizaion.and differentiation potential Cytotherapy 2003; , 5 (5) : 362-9. Schweiz Monatsschr Zahnmed Ulmer FL 20 860 2010 Ulmer FL, Winkel A, Kohorst P, Stiesch M. Stem cells--prospects in dentistry Schweiz Monatsschr Zahnmed 2010; 20 (10) : 860-3. J Vis Exp Langer R. Vacanti JP 2009 Langer R. Vacanti JP , Burdick J. Cellular encapsulation in 3D hydrogels for tissue engineering J Vis Exp 2009; (32): J Vis Exp Khetan S pii. 1590 2009 Khetan S, Burdick J. Cellular encapsulation in 3D hydrogels for tissue engineering J Vis Exp 2009; (32): pii. 1590-. Biomaterials Schneider RK 31 467 2010 Schneider RK, Puellen A, Kramann R, et al. The osteogenic differentiation of adult bone marrow and perinatal umbilical mesenchymal stem cells and matrix remodelling in three-dimensional collagen scaffolds Biomaterials 2010; 31 (3) : 467-80. J Dent Res Young CS 81 695 2002 Young CS, Terada S, Vacanti JP, Honda M, Bartlett JD, Yelick PC. Tissue engineering of complex tooth structures on biodegradable polymer scaffolds J Dent Res 2002; 81 (10) : 695-700. Arch Oral Biol Honda MJ 51 282 2006 Honda MJ, Shimodaira T, Ogaeri T, Shinohara Y, Hata K, Ueda M. A novel culture system for porcine odontogenic epithelial cells using a feeder layer Arch Oral Biol 2006; 51 (4) : 282-90. Biomaterials Honda MJ 28 680 2007 Honda MJ, Tsuchiya S, Sumita Y, Sagara H, Ueda M. The sequential seeding of epithelial and mesenchymal cells for tissue-engineered tooth regeneration Biomaterials 2007; 28 (4) : 680-9. Exp Hematol Friedenstein AJ 4 267 1976 Friedenstein AJ, Gorskaja JF, Kulagina NN. Fibroblast precursors in normal and irradiated mouse hematopoietic organs Exp Hematol 1976; 4 (5) : 267-74. Cytotherapy Dominici M 8 315 2006 Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells.The International Society for Cellular Therapy position statement Cytotherapy 2006; 8 (4) : 315-7. Science Prockop DJ 276 71 1997 Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues Science 1997; 276 (5309) : 71-4. Proc Natl Acad Sci USA Gronthos S 97 13625 2000 Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Proc Natl Acad Sci USA 2000; 97 (25) : 13625-30. Proc Natl Acad Sci USA Miura M 100 5807 2003 Miura M, Gronthos S, Zhao M, et al. SHED stem cells from human exfoliated deciduous teeth Proc Natl Acad Sci USA 2003; 100 (10) : 5807-12. Lancet Seo BM 364 149 2004 Seo BM, Miura M, Gronthos S, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament Lancet 2004; 364 (9429) : 149-55. Matrix Biol Morsczeck C 24 155 2005 Morsczeck C, Gotz W, Schierholz J, et al. Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth Matrix Biol 2005; 24 (2) : 155-65. PLoS ONE Sonoyama W 1 e 79 2006 Sonoyama W, Liu Y, Fang D, et al. Mesenchymal stem cell-mediated functional tooth regeneration in swine PLoS ONE 2006; 1 : e 79-0. J Dent Res Gronthos S 81 531 2002 Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells J Dent Res 2002; 81 (8) : 531-. Cell Biol Int Otaki S 31 1191 2007 Otaki S, Ueshima S, Shiraishi K, et al. Mesenchymal progenitor cells in adult human dental pulp and their ability to form bone when transplanted into immunocompromised mice Cell Biol Int 2007; 31 (10) : 1191-7. J Cell Physiol Papaccio G 208 319 2006 Papaccio G, Graziano A, d'Aquino R, et al. Long-term cryopreservation of dental pulp stem cells (SBP-DPSCs) and their differentiated osteoblasts: a cell source for tissue repair J Cell Physiol 2006; 208 (2) : 319-25. J Endod Ishkitiev N 36 469 2010 Ishkitiev N, Yaegaki K, Calenic B, et al. Deciduous and permanent dental pulp mesenchymal cells acquire hepatic morphologic and functional features in vitro J Endod 2010; 36 (3) : 469-74. Biomaterials Zhang W 27 5658 2006 Zhang W, Walboomers XF, van Kuppevelt TH, Daamen WF, Bian Z, Jansen JA. The performance of human dental pulp stem cells on different three-dimensional scaffold materials Biomaterials 2006; 27 (33) : 5658-68. Stem Cells Dev Murray PE 13 255 2004 Murray PE, Garcia-Godoy F. Stem cell responses in tooth regeneration Stem Cells Dev 2004; 13 (3) : 255-62. Oral Dis Sloan AJ 13 151 2007 Sloan AJ, Smith AJ. Stem cells and the dental pulp: potential roles in dentine regeneration and repair Oral Dis 2007; 13 (2) : 151-7. J Endod Cordeiro MM 34 962 2008 Cordeiro MM, Dong Z, Kaneko T, et al. Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth J Endod 2008; 34 (8) : 962-. J Dent Res Seo BM 84 907 2005 Seo BM, Miura M, Sonoyama W, Coppe C, Stanyon R, Shi S. Recovery of stem cells from cryopreserved periodontal ligament J Dent Res 2005; 84 (10) : 907-12. Orthod Craniofac Res Gay IC 10 149 2007 Gay IC, Chen S, MacDougall M. Isolation and characterization of multipotent human periodontal ligament stem cells Orthod Craniofac Res 2007; 10 (3) : 149-60. Stem Cells Liu Y 26 1065 2008 Liu Y, Zheng Y, Ding G, et al. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine Stem Cells 2008; 26 (4) : 1065-73. Acta Histochem Orciani M 111 15 2009 Orciani M, Trubiani O, Vignini A, Mattioli-Belmonte M, Di Primio R, Salvolini E. Nitric oxide production during the osteogenic differentiation of human periodontal ligament mesenchymal stem cells Acta Histochem 2009; 111 (1) : 15-24. J Periodontal Res Yang ZH 44 199 2009 Yang ZH, Zhang XJ, Dang NN, et al. Apical tooth germ cell-conditioned medium enhances the differentiation of periodontal ligament stem cells into cementum/periodontal ligament-like tissues J Periodontal Res 2009; 44 (2) : 199-210. J Periodontal Res Coura GS 43 531 2008 Coura GS, Garcez RC, de Aguiar CB, Alvarez-Silva M, Magini RS, Trentin AG. Human periodontal ligament: a niche of neural crest stem cells J Periodontal Res 2008; 43 (5) : 531-6. Cell Tissue Res Kemoun P 329 283 2007 Kemoun P, Laurencin-Dalicieux S, Rue J, et al. Human dental follicle cells acquire cementoblast features under stimulation by BMP-2/-7 and enamel matrix derivatives (EMD) in vitro Cell Tissue Res 2007; 329 (2) : 283-94. J Dent Res Yao S 87 767 2008 Yao S, Pan F, Prpic V, Wise GE. Differentiation of stem cells in the dental follicle J Dent Res 2008; 87 (8) : 767-1. Connect Tissue Res Handa K 43 406 2002 Handa K, Saito M, Tsunoda A, et al. Progenitor cells from dental follicle are able to form cementum matrix in vivo Connect Tissue Res 2002; 43 (2-3) : 406-8. Cell Tissue Res Yokoi T 327 301 2007 Yokoi T, Saito M, Kiyono T, et al. Establishment of immortalized dental follicle cells for generating periodontal ligament in vivo Cell Tissue Res 2007; 327 (2) : 301-11. Cell Tissue Res Kikuchi H 317 173 2004 Kikuchi H, Suzuki K, Sakai N, Yamada S. Odontoblasts induced from mesenchymal cells of murine dental papillae in three-dimensional cell culture Cell Tissue Res 2004; 317 (2) : 173-85. Biochem Biophys Res Commun Ikeda E 342 1257 2006 Ikeda E, Hirose M, Kotobuki N, et al. Osteogenic differentiation of human dental papilla mesenchymal cells Biochem Biophys Res Commun 2006; 342 (4) : 1257-62. Differentiation Amar S 41 56 1989 Amar S, Luo W, Snead ML, Ruch JV. Amelogenin gene expression in mouse incisor heterotopic recombinations Differentiation 1989; 41 (1) : 56-61. Dev Dyn Yoshiba K 211 164 1998 Yoshiba K, Yoshiba N, Aberdam D, et al. Expression and localization of laminin-5 subunits during mouse tooth development Dev Dyn 1998; 211 (2) : 164-76. Cell Transplant Honda MJ 16 833 2007 Honda MJ, Shinohara Y, Hata KI, Ueda M. Subcultured odontogenic epithelial cells in combination with dental mesenchymal cells produce enamel-dentin-like complex structures Cell Transplant 2007; 16 (8) : 833-47. Tissue Eng Hu B 12 2069 2006 Hu B, Nadiri A, Kuchler-Bopp S, Perrin-Schmitt F, Peters H, Lesot H. Tissue engineering of tooth crown.oot.and periodontium Tissue Eng 2006; 12 (8) : 2069-75. Nat Methods Nakao K 4 227 2007 Nakao K, Morita R, Saji Y, et al. The development of a bioengineered organ germ method Nat Methods 2007; 4 (3) : 227-30. Proc Natl Acad Sci USA Ikeda E 106 13475 2009 Ikeda E, Morita R, Nakao K, et al. Fully functional bioengineered tooth replacement as an organ replacement therapy Proc Natl Acad Sci USA 2009; 106 (32) : 13475-80. Eur Cell Mater d'Aquino R 18 75 2009 d'Aquino R, De Rosa A, Lanza V, et al. Human mandible bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes Eur Cell Mater 2009; 18 : 75-83.