<?xml version="1.0"?>
<doi_batch xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.crossref.org/schema/4.4.0" xmlns:fr="http://www.crossref.org/fundref.xsd" xmlns:ct="http://www.crossref.org/clinicaltrials.xsd" xmlns:ai="http://www.crossref.org/AccessIndicators.xsd" xmlns:rel="http://www.crossref.org/relations.xsd" xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1" version="4.4.0" xsi:schemaLocation="http://www.crossref.org/schema/4.4.0 crossref4.4.0.xsd">
  <head>
    <doi_batch_id>TODENTJ-25-03-2019_TODENTJ-6-56</doi_batch_id>
    <timestamp>1553505321</timestamp>
    <depositor>
      <depositor_name>Bentham Open</depositor_name>
      <email_address>doi@benthamopen.net</email_address>
    </depositor>
    <registrant>Bentham Open</registrant>
  </head>
  <body>
    <journal>
      <journal_metadata language="en">
        <full_title>The Open Dentistry Journal</full_title>
        <abbrev_title>TODENTJ</abbrev_title>
        <issn media_type="print">1874-2106</issn>
      </journal_metadata>
      <journal_issue>
        <publication_date media_type="print">
          <month>3</month>
          <day>16</day>
          <year>2012</year>
        </publication_date>
        <journal_volume>
          <volume>6</volume>
        </journal_volume>
        <issue>1</issue>
      </journal_issue>
      <journal_article publication_type="full_text">
        <titles>
          <title>The Effect of Exercise on Pulpal and Gingival Blood Flow in Physically Active and Inactive Subjects as Assessed by Laser Doppler</title>
        </titles>
        <contributors>
          <person_name contributor_role="author" sequence="first">
            <given_name>EC</given_name>
            <surname>Lobo</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>SMT</given_name>
            <surname>Nguyen </surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>MA</given_name>
            <surname>Pogrel</surname>
          </person_name>
        </contributors>
        <jats:abstract>
                <jats:p>The effects of exercise on pulpal and gingival blood flow are undefined. The autonomic nervous system response suggests that they could increase or decrease with exercise, and they may be independent of each other. This study attempts to answer these questions.</jats:p>
                <jats:sec>
                    <jats:title>Materials and Methods:</jats:title>
                    <jats:p>15 “physically active” subjects and 15 “physically inactive” subjects exercised on a treadmill. Laser Doppler recordings of pulpal and gingival blood flow were taken before and after exercise.</jats:p>
                </jats:sec>
                <jats:sec>
                    <jats:title>Results:</jats:title>
                    <jats:p>There was a mean increase of approximately 50% in both pulpal (range -66%-+509%) and gingival (-72%- +1022%) blood flow after exercise, with wide variations, with no significant differences between the two groups of subjects.</jats:p>
                </jats:sec>
                <jats:sec>
                    <jats:title>Conclusion:</jats:title>
                    <jats:p>Exercise could increase pulpal and/or gingival blood flow as part of the overall increase in cardiac output with exercise, or could decrease pulpal and/or gingival blood flow due to diversion of blood to the somatic muscles during exercise. This study suggests that the former physiological phenomenon usually takes place at both sites,though there were some contradictory results.</jats:p>
            </jats:sec>
            </jats:abstract>
        <publication_date>
          <month>3</month>
          <day>16</day>
          <year>2012</year>
        </publication_date>
        <pages>
          <first_page>56</first_page>
          <last_page>60</last_page>
        </pages>
        <publisher_item>
          <identifier id_type="sici">TODENTJ-6-56</identifier>
        </publisher_item>
        <crossmark>
          <crossmark_version>1</crossmark_version>
          <crossmark_policy>10.2174/crossmark_policy</crossmark_policy>
          <crossmark_domains>
            <crossmark_domain>
              <domain>opendentistryjournal.com</domain>
            </crossmark_domain>
            <crossmark_domain>
              <domain>benthamopen.com</domain>
            </crossmark_domain>
          </crossmark_domains>
          <crossmark_domain_exclusive>true</crossmark_domain_exclusive>
          <custom_metadata>
            <assertion name="review_status" label="Review Status" group_name="peer_review_details" group_label="Peer Review Details" order="0">Peer Reviewed</assertion>
            <assertion name="review_process" label="Review Process" group_name="peer_review_details" group_label="Peer Review Details" order="1">Single blind</assertion>
            <assertion name="screening_status" label="Screening Status" group_name="plagiarism_screening" group_label="Plagiarism Screening" order="0">Checked with iThenticate</assertion>
            <assertion name="received" label="Received" group_name="publication_history" group_label="Publication History" order="0">2011-11-29</assertion>
            <assertion name="revised" label="Revised" group_name="publication_history" group_label="Publication History" order="1">2012-1-19</assertion>
            <assertion name="accepted" label="Accepted" group_name="publication_history" group_label="Publication History" order="2">2012-1-30</assertion>
            <assertion name="published" label="Published" group_name="publication_history" group_label="Publication History" order="3">2012-3-16</assertion>
            <ai:program name="AccessIndicators">
              <ai:license_ref>http://creativecommons.org/licenses/by-nc/3.0/</ai:license_ref>
            </ai:program>
          </custom_metadata>
        </crossmark>
        <doi_data>
          <doi>10.2174/1874210601206010056</doi>
          <timestamp>1553505321</timestamp>
          <resource>https://opendentistryjournal.com/VOLUME/6/PAGE/56/</resource>
          <collection property="crawler-based">
            <item crawler="google">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item crawler="msn">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item crawler="altavista">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item crawler="yahoo">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item crawler="scirus">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item crawler="iParadigms">
              <resource>https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
          </collection>
          <collection property="text-mining">
            <item>
              <resource mime_type="application/pdf">https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.pdf</resource>
            </item>
            <item>
              <resource mime_type="application/xml">https://opendentistryjournal.com/contents/volumes/V6/TODENTJ-6-56/TODENTJ-6-56.xml</resource>
            </item>
          </collection>
        </doi_data>
        <citation_list>
          <citation key="refR1">
            <journal_title>Acta Physiol Scand</journal_title>
            <author>Aars H</author>
            <volume>148</volume>
            <first_page>441</first_page>
            <cYear>1993</cYear>
            <unstructured_citation>
                Aars H, Brodin P, Andersen E. 
                A study of cholinergic and beta-adrenergic components in the regulation of blood flow in the tooth pulp and gingiva in man 
                Acta Physiol Scand  
                1993; 
                148
                : 441-7.
                
            </unstructured_citation>
          </citation>
          <citation key="refR2">
            <journal_title>Acta Physiol Scand</journal_title>
            <author> Aars H</author>
            <volume>140</volume>
            <first_page>7A</first_page>
            <cYear>1990</cYear>
            <unstructured_citation>
                 Aars H, Gazelius B, Edwall L, Olgart L. 
                Nervous control of blood flow in the human tooth 
                Acta Physiol Scand  
                1990; 
                140
                : 7A.
            </unstructured_citation>
          </citation>
          <citation key="refR3">
            <journal_title>Acta Physiol Scand</journal_title>
            <author> Aars H</author>
            <volume>146</volume>
            <first_page>423</first_page>
            <cYear>1992</cYear>
            <unstructured_citation>
                 Aars H, Gazelius B, Edwall L, Olgart L. 
                Effects of autonomic reflexes on tooth pulp blood flow in man 
                Acta Physiol Scand  
                1992; 
                146
                : 423-9.
                
            </unstructured_citation>
          </citation>
          <citation key="refR4">
            <unstructured_citation>
                 Costill D, Wilmore JH. 
                Physiology of Sport and Exercise.  3rd. 
                Champaign Illinois: Human Kinetics Publishers 2004; 50: pp. 
                
                
                
                
                566-602.
                
            </unstructured_citation>
          </citation>
          <citation key="refR5">
            <journal_title>J Dent Res</journal_title>
            <author> Ramsay DS</author>
            <volume>70</volume>
            <first_page>1427</first_page>
            <cYear>1991</cYear>
            <unstructured_citation>
                 Ramsay DS, Artun J, Martinen SS. 
                Reliability of pulpal blood-flow
measurements utilizing laser Doppler flowmetry 
                J Dent Res  
                1991; 
                70
                : 1427-30.
                
            </unstructured_citation>
          </citation>
          <citation key="refR6">
            <journal_title>Crit Rev Oral Biol Med</journal_title>
            <author> Olgart L</author>
            <volume>7</volume>
            <first_page>159</first_page>
            <cYear>1996</cYear>
            <unstructured_citation>
                 Olgart L. 
                Neural control of pulpal blood flow 
                Crit Rev Oral Biol Med  
                1996; 
                7
                : 159-71.
                
            </unstructured_citation>
          </citation>
          <citation key="refR7">
            <journal_title>J Appl Physiol</journal_title>
            <author> Thomas GD</author>
            <volume>97</volume>
            <first_page>731</first_page>
            <cYear>2004</cYear>
            <unstructured_citation>
                 Thomas GD, Segal SS. 
                Neural control of muscle blood flow during exercise 
                J Appl Physiol  
                2004; 
                97
                : 731-8.
                
            </unstructured_citation>
          </citation>
          <citation key="refR8">
            <journal_title>Brain Res</journal_title>
            <author> Kemppainen P</author>
            <volume>360</volume>
            <first_page>33</first_page>
            <cYear>1985</cYear>
            <unstructured_citation>
                 Kemppainen P, Pertovaara A, Huopaniemi T, Johansson G, Karonen SL. 
                Modification of dental pain and cutaneous thermal sensitivity by physical exercise in man 
                Brain Res  
                1985; 
                360
                : 33-40.
                
            </unstructured_citation>
          </citation>
          <citation key="refR9">
            <journal_title>Br Dent J</journal_title>
            <author> Steel B</author>
            <volume>208</volume>
            <first_page>380</first_page>
            <cYear>2010</cYear>
            <unstructured_citation>
                 Steel B. 
                Running pain 
                Br Dent J  
                2010; 
                208
                (9
                )
                : 380.
            </unstructured_citation>
          </citation>
          <citation key="refR10">
            <unstructured_citation>
                Arnall D. 
                ACSM's guidelines for exercise testhing and prescription 
                available from http://~jan.ucc.nau.edu/daa/ACSMGuidelines/ 
                2000.
            </unstructured_citation>
          </citation>
          <citation key="refR11">
            <journal_title>Arch Oral Biol</journal_title>
            <author> Soo-ampon S</author>
            <volume>48</volume>
            <first_page>353</first_page>
            <cYear>2003</cYear>
            <unstructured_citation>
                 Soo-ampon S, Vongsavan N, Soo-ampon M, Chuckpaiwong S, Matthews B. 
                The sources of laser Doppler blood-flow signals recorded from human teeth 
                Arch Oral Biol  
                2003; 
                48
                : 353-60.
                
            </unstructured_citation>
          </citation>
          <citation key="refR12">
            <journal_title>Arch Oral Biol</journal_title>
            <author> Vongsavan N</author>
            <volume>41</volume>
            <first_page>97</first_page>
            <cYear>1996</cYear>
            <unstructured_citation>
                 Vongsavan N, Matthews B. 
                Experiments in pigs on the sources of laser Doppler blood-flow signals recorded from teeth 
                Arch Oral Biol  
                1996; 
                41
                : 97-103.
                
            </unstructured_citation>
          </citation>
          <citation key="refR13">
            <journal_title>J Oral Maxillofac Surg</journal_title>
            <author> Dodson TB</author>
            <volume>55</volume>
            <first_page>51</first_page>
            <cYear>1997</cYear>
            <unstructured_citation>
                 Dodson TB, Bays RA, Neuenschwander MC. 
                Maxillary perfusion during Le Fort I osteotomy after ligation of the descending palatine artery 
                J Oral Maxillofac Surg  
                1997; 
                55
                : 51-.
                
            </unstructured_citation>
          </citation>
          <citation key="refR14">
            <journal_title>Endod Dent Traumatol</journal_title>
            <author> Gazelius B</author>
            <volume>4</volume>
            <first_page>265</first_page>
            <cYear>1988</cYear>
            <unstructured_citation>
                 Gazelius B, Olgart L, Edwall B. 
                Restored vitality in luxated teeth assessed by laser Doppler flowmeter 
                Endod Dent Traumatol  
                1988; 
                4
                : 265-8.
                
            </unstructured_citation>
          </citation>
          <citation key="refR15">
            <journal_title>Endod Dent Traumatol</journal_title>
            <author> Gazelius B</author>
            <volume>2</volume>
            <first_page>219</first_page>
            <cYear>1986</cYear>
            <unstructured_citation>
                 Gazelius B, Olgart L, Edwall B, Edwall L. 
                Non-invasive recording of blood flow in human dental pulp 
                Endod Dent Traumatol  
                1986; 
                2
                : 219-.
                
            </unstructured_citation>
          </citation>
          <citation key="refR16">
            <journal_title>Int Endod J</journal_title>
            <author> Olgart L</author>
            <volume>2</volume>
            <first_page>300</first_page>
            <cYear>1988</cYear>
            <unstructured_citation>
                 Olgart L, Gazelius B, Lindh-Stromberg U. 
                Laser Doppler flowmetry in assessing vitality in luxated permanent teeth 
                Int Endod J  
                1988; 
                2
                : 300-6.
                
            </unstructured_citation>
          </citation>
          <citation key="refR17">
            <journal_title>Oral Surg Oral Med Oral Pathol Oral Radiol Endod</journal_title>
            <author> Ahn J</author>
            <first_page>197</first_page>
            <cYear>1998</cYear>
            <unstructured_citation>
                 Ahn J, Pogrel MA. 
                The effects of 2% lidocaine with 1:100000 epinephrine on pulpal and gingival blood flow 
                Oral Surg Oral Med Oral Pathol Oral Radiol Endod  
                1998; 
                197-202.
                
            </unstructured_citation>
          </citation>
          <citation key="refR18">
            <journal_title>Clin Hemorheol Microcirc</journal_title>
            <author> Amatyakul S</author>
            <volume>34</volume>
            <first_page>295</first_page>
            <cYear>2006</cYear>
            <unstructured_citation>
                 Amatyakul S, Chakraphan D, Chotipaibulpan S, Patumraj S. 
                Role of exercise training on pulpal blood flow in diabetic rats 
                Clin Hemorheol Microcirc  
                2006; 
                34
                : 295-301.
                
            </unstructured_citation>
          </citation>
          <citation key="refR19">
            <journal_title>Int Endod J</journal_title>
            <author> Watson AD</author>
            <volume>25</volume>
            <first_page>82</first_page>
            <cYear>1992</cYear>
            <unstructured_citation>
                 Watson AD, Pitt Ford TR, McDonald F. 
                Blood flow changes in the dental pulp during limited exercise measured by laser Doppler flowmetry 
                Int Endod J  
                1992; 
                25
                : 82-7.
                
            </unstructured_citation>
          </citation>
        </citation_list>
      </journal_article>
    </journal>
  </body>
</doi_batch>
