TODENTJ-25-03-2019_TODENTJ-5-146 1553505272 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 8 27 2011 5 1 Yumiko Tomoyasu Kazuo Mukae Michiyo Suda Tomoko Hayashi Minako Ishii Mai Sakaguchi Yoshihisa Watanabe Ayako Jinzenji Yukiko Arai Hitoshi Higuchi Shigeru Maeda Takuya Miyawaki Some dental patients have histories of adverse reactions to local anesthesia. The aim of the present study was to investigate the frequency of allergy to local anesthetics of dental patients who had histories of adverse reactions to local anesthesia based on the results of allergy tests in our institute over a period of 5 years. We investigated the past medical records of dental patients retrospectively, and twenty patients were studied. Three of the 20 showed a positive or false-positive reaction in the intracutaneous test, and one patient showed a false-positive reaction in the challenge test. Our results suggest that the frequency of allergy to local anesthetics is low even if patients have histories of adverse reactions to local anesthesia. However, allergy tests of local anesthetics should be performed in patients in whom it is uncertain whether they are allergic. 8 27 2011 146 149 TODENTJ-5-146 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2011-5-10 2011-7-25 2011-7-27 2011-8-27 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210601105010146 1553505272 https://opendentistryjournal.com/VOLUME/5/PAGE/146/ https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.pdf https://opendentistryjournal.com/contents/volumes/V5/TODENTJ-5-146/TODENTJ-5-146.xml J Am Dent Assoc Giovannitti JA 98 701 1979 Giovannitti JA, Bennett CR. Assessment of allergy to local anesthetics J Am Dent Assoc 1979; 98 : 701-6. Ann Allergy Asthma Immunol Berkun Y 91 342 2003 Berkun Y, Ben-Zvi A, Levy Y, Galili D, Shalit M. Evaluation of adverse reactions to local anesthetics: experience with 236 patients Ann Allergy Asthma Immunol 2003; 91 : 342-5. Anesth Pain Control Dent Malamed SF 1 11 1992 Malamed SF, Sykes P, Kubota Y, Matsuura H, Lipp M. Local anesthesia: a review Anesth Pain Control Dent 1992; 1 : 11-24. South Med J Adriani J 74 694 1981 Adriani J, Zepernick R. Allergic reactions to local anesthetics South Med J 1981; 74 : 694-9703. Int Anesthesiol Clin Adriani J 10 127 1972 Adriani J. Etiology and management of adverse reactions to local anesthetics Int Anesthesiol Clin 1972; 10 : 127-51. Anaesth Intensive Care Fisher MM 25 611 1997 Fisher MM, Bowey CJ. Alleged allergy to local anaesthetics Anaesth Intensive Care 1997; 25 : 611-4. Monheim LM. Monheim's local anesthesia and pain control in dental practice. St Louis: Mosby Co 1978; pp. 162-6. Br Dent J Wildsmith JA 184 507 1998 Wildsmith JA, Mason A, McKinnon RP, Rae SM. Alleged allergy to local anaesthetic drugs Br Dent J 1998; 184 : 507-10. J Emerg Nurs Kelly KJ 24 539 1998 Kelly KJ, Walsh-Kelly CM. Latex allergy: a patient and health care system emergency J Emerg Nurs 1998; 24 : 539-45. J Allergy Clin Immunol Schwartz HJ 75 525 1985 Schwartz HJ, Sher TH. Bisulfite sensitivity manifesting as allergy to local dental anesthesia J Allergy Clin Immunol 1985; 75 : 525-7. Contact Dermatitis Barbaud A 45 321 2001 Barbaud A, Goncalo M, Bruynzeel D, Bircher A. Guidelines for performing skin tests with drugs in the investigation of cutaneous adverse drug reactions Contact Dermatitis 2001; 45 : 321-8. J Allergy Clin Immunol Schatz M 74 606 1984 Schatz M. Skin testing and incremental challenge in the evaluation of adverse reactions to local anesthetics J Allergy Clin Immunol 1984; 74 : 606-16. Anaesth Intensive Care Fisher MM 7 58 1979 Fisher MM. Intradermal testing in the diagnosis of acute anaphylaxis during anaesthesia--results of five years experience Anaesth Intensive Care 1979; 7 : 58-61. Anesth Analg Aldrete JA 49 173 1970 Aldrete JA, Johnson DA. Evaluation of intracutaneous testing for investigation of allergy to local anesthetic agents Anesth Analg 1970; 49 : 173-83. Ann Emerg Med Green SM 23 1284 1994 Green SM, Rothrock SG, Gorchynski J. Validation of diphenhydramine as a dermal local anesthetic Ann Emerg Med 1994; 23 : 1284-9. Contact Dermatitis Thyssen JP 59 69 2008 Thyssen JP, Menne T, Elberling J, Plaschke P, Johansen JD. Hypersensitivity to local anaesthetics--update and proposal of evaluation algorithm Contact Dermatitis 2008; 59 : 69-78.