Clinical and Histological Comparison of Extraction Socket Healing Following the Use of Autologous Platelet-Rich Fibrin Matrix (PRFM) to Ridge Preservation Procedures Employing Demineralized Freeze Dried Bone Allograft Material and Membrane

TODENTJ-25-03-2019_TODENTJ-3-92 1553505058 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 5 20 2009 3 1 Clinical and Histological Comparison of Extraction Socket Healing Following the Use of Autologous Platelet-Rich Fibrin Matrix (PRFM) to Ridge Preservation Procedures Employing Demineralized Freeze Dried Bone Allograft Material and Membrane B.I Simon A.L Zatcoff J.J.W Kong S.M O’Connell Background: The healing potential of platelet growth factors has generated interest in using Platelet-Rich Plasma (PRP) in ridge preservation procedures. A canine study was performed to determine if extraction sites treated with platelet-rich fibrin matrix (PRFM) exhibit enhanced healing compared to sites treated with non-viable materials. Methods: Four dog’s extraction sockets were treated individually with PRFM, PRFM and membrane, Demineralized Freeze-Dried Bone Allograft (DFDBA) and membrane, PRFM and DFDBA, and untreated control. Treatment sequencing permitted clinical and histologic evaluation of healing at 10 days, 2, 3, 6 and 12 weeks. Results: Healing was more rapid in the PRFM and PRFM and membrane sites. By 3 weeks those sockets had osseous fill. Sites containing DFDBA had little new bone at 6 weeks. By 12 weeks those sockets had osseous fill but DFDBA particles were still noted in coronal areas. Conclusions: PRFM alone may be the best graft for ridge preservation procedures. Advantages: faster healing, and elimination of disadvantages involved in using barrier membranes. 5 20 2009 92 99 TODENTJ-3-92 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2008-12-5 2009-1-4 2009-3-17 2009-5-20 http://creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210600903010092 1553505058 https://opendentistryjournal.com/VOLUME/3/PAGE/92/ https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-92/TODENTJ-3-92.xml Scand J Plast Reconstr Hand Surg Dahlin C 24 13 1990 Dahlin C, Gottlow J, Linde A, et al. 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