TODENTJ-25-03-2019_TODENTJ-3-125 1553505068 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 6 09 2009 3 1 L.A Gonçalves S.C Boldrini T.S.O Capote C.B Binotti R.A Azeredo D.T Martini B Rosenberg W.G Bautz E.A Liberti The effects of protein malnutrition, both in utero and prior to weaning, on formation of the first mandibular molars were evaluated by phase-contrast and electron microscopy in rats. The nourished group (GI) received a diet that included 20% casein, while the malnourished group (GII) received 5% casein. The first mandibular molars from GII exhibited low density of cells and odontoblasts, which lacked regular organization compared with molars from GI. In addition, a difference in collagen type was observed between the groups, with a prevalence of Type III collagen fibers detected in the dentin, periodontal ligament, and alveolar bone of GII, and a prevalence of Type I collagen fibers in GI. Finally, examination of surface area in molar sagittal sections indicated 30% less dentin in GII, compared with GI. Our results suggest that structural and ultra-structural features of the dentin-pulp complex and periodontal components of rat molars are affected by protein deficiency. 6 09 2009 125 131 TODENTJ-3-125 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2008-10-22 2009-2-26 2009-4-8 2009-6-09 http: //creativecommons.org/licenses/by-nc/3.0/ 10.2174/1874210600903010125 1553505068 https://opendentistryjournal.com/VOLUME/3/PAGE/125/ https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.pdf https://opendentistryjournal.com/contents/volumes/V3/TODENTJ-3-125/TODENTJ-3-125.xml J Nutr Zeman FJ 93 167 1967 Zeman FJ. 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