TODENTJ-25-03-2019_TODENTJ-12-80 1553507281 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 01 31 2018 12 1 Mathilde Fénelon Sabine Castet Jean-Christophe Fricain Sylvain Catros Introduction: Von Willebrand Disease is the most common inherited bleeding disorder. In the general population, 1/8000 patients are affected. Primary hemostasis (platelet adhesion) and coagulation (protection of Factor VIII) are altered. Among several bleeding symptoms, these patients suffer from excessive bleeding of oral mucosa and dental management requires a close collaboration between haematologists and oral surgeons. Materials & Methods: Guided implant surgery can be used to increase the accuracy of implant placement and to reduce the overall morbidity of this surgical procedure by using a flapless surgery technique. Case Report: We report the case of a 49 years old woman having a Type 2A von Willebrand disease and who presented to replace tooth #.46 because of interradicular fracture and peri-apical infection. After planning the implant surgery using Codiagnostix® software, a surgical guide was prepared. The patient received 4 injections of von Willebrand factor (Willfactin®) for this particular surgical procedure. The implant was placed immediately after tooth removal and local haemostasis was performed. Discussion: The follow-up was uneventful and the implant was restored by a crown 4 months later. Two cases of implant placement in haemophiliac patients have been reported before in the literature. Conclusion: As far as we know, this is the first case report of implant placement in a patient having a von Willebrand disease. The use of guided surgery allowed to perform a mini-invasive procedure and thus contributed to prevent bleeding complications in this patient. 01 31 2018 80 86 TODENTJ-12-80 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2017-11-17 2017-12-20 2018-01-05 2018-01-31 https://creativecommons.org/licenses/by/4.0/legalcode 10.2174/1874210601812010080 1553507281 https://opendentistryjournal.com/VOLUME/12/PAGE/80/ https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-80/TODENTJ-12-80.xml N. 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