TODENTJ-25-03-2019_TODENTJ-12-614 1553507476 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 09 28 2018 12 1 Silvia Cerroni Guido Pasquantonio Roberta Condò Loredana Cerroni Background: Periodontal implications of orthodontic therapy are frequent, gingival and periodontal conditions need to be evaluated for every appointment. Several studies have analyzed the effects of fixed appliance on periodontal health. Objective: To evaluate whether there is updated scientific evidence on the relationship between fixed orthodontic therapy and periodontal health. Methods: A literature search was performed using the Pubmed and Cochrane databases and manual search; the search was carried out using the keywords “orthodontic” and “periodontal”. Articles published only in the English language from January 1997 to April 2017 were included. The inclusion criteria were: RCTs, cohort studies, cross-sectional studies and case-control studies only in English language; only studies on humans, with a minimum sample size of 20 patients and no restriction in terms of patient ages; orthodontic fixed appliances placed into the buccal tooth surface; standardization and training in oral hygiene; Periodontal Index (PI), Gingival Index (GI), Bleeding on Probing (BOP), Pocket Probing Depth (PPD), at least at baseline (before appliance was placed) and after follow up (with a minimum period of 3 months). The exclusion criteria were as follows: absence of baseline data before fixed appliances was placed; patients with systemic diseases, periodontal disease or craniofacial anomalies; removable appliances or orthodontic appliance on the lingual dental surface; and no standardization or training in oral hygiene. Studies were selected by abstract and title; then, inclusion and exclusion criteria were applied. The studies that satisfied the inclusion criteria were evaluated and classified as having low, moderate or high methodology quality. Results: Fifty-five records were reviewed on the basis of title and abstract. After full-text reading, 47 full texts were excluded, and 3 articles were classified as having low methodological quality and 5 as having moderate methodological quality. Conclusions: The present systematic analysis suggests that there is moderate scientific evidence that a fixed appliance influences periodontal status; no article reported a high score. 09 28 2018 614 622 TODENTJ-12-614 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2018-4-30 2018-7-26 2018-9-13 2018-09-28 https://creativecommons.org/licenses/by/4.0/legalcode 10.2174/1745017901814010614 1553507476 https://opendentistryjournal.com/VOLUME/12/PAGE/614/ https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.pdf https://opendentistryjournal.com/contents/volumes/V12/TODENTJ-12-614/TODENTJ-12-614.xml J. Am. Dent. Assoc. Bollen A.M. 139 413 2008 10.14219/jada.archive.2008.0184 Bollen AM, Cunha-Cruz J, Bakko DW, Huang GJ, Hujoel PP. The effects of orthodontic therapy on periodontal health: A systematic review of controlled evidence. J Am Dent Assoc 2008; 139 (4) : 413-22. J. Periodontol. Atack N.E. 67 78 1996 10.1902/jop.1996.67.2.78 Atack NE, Sandy JR, Addy M. Periodontal and microbiological changes associated with the placement of orthodontic appliances. A review. J Periodontol 1996; 67 (2) : 78-85. J. Periodontol. Bogren A. 78 1708 2007 10.1902/jop.2007.070028 Bogren A, Teles RP, Torresyap G, Haffajee AD, Socransky SS, Wennström JL. Clinical and microbiologic changes associated with the combined use of a powered toothbrush and a triclosan/copolymer dentifrice: A 3-year prospective study. J Periodontol 2007; 78 (9) : 1708-17. Oral Implantol. (Rome) Condò R. 5 92 2013 Condò R, Casaglia A, Condò SG, Cerroni L. Plaque retention on elastomeric ligatures. An in vivo study. Oral Implantol (Rome) 2013; 5 (4) : 92-9. Dental Press J. Orthod. Freitas A.O. 19 46 2014 10.1590/2176-9451.19.2.046-055.oar Freitas AO, Marquezan M, Nojima MdaC, Alviano DS, Maia LC. The influence of orthodontic fixed appliances on the oral microbiota: A systematic review. Dental Press J Orthod 2014; 19 (2) : 46-55. Am. J. Orthod. Dentofacial Orthop. Glans R. 124 679 2003 10.1016/j.ajodo.2003.05.001 Glans R, Larsson E, Øgaard B. Longitudinal changes in gingival condition in crowded and noncrowded dentitions subjected to fixed orthodontic treatment. Am J Orthod Dentofacial Orthop 2003; 124 (6) : 679-82. J. Clin. Epidemiol. Moher D. 62 1006 2009 10.1016/j.jclinepi.2009.06.005 Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. J Clin Epidemiol 2009; 62 (10) : 1006-12. J. Indian Soc. Periodontol. Dannan A. 14 66 2010 10.4103/0972-124X.65445 Dannan A. An update on periodontic-orthodontic interrelationships. J Indian Soc Periodontol 2010; 14 (1) : 66-71. Preoteasa CT, Ionescu E, Preoteasa E. Risks and Complications Associated with Orthodontic Treatment. In: Basic Aspects and Clinical Considerations, Farid Bourzgui, Eds. 2012. Saudi Dent. J. Talic N.F. 23 55 2011 10.1016/j.sdentj.2011.01.003 Talic NF. Adverse effects of orthodontic treatment: A clinical perspective. Saudi Dent J 2011; 23 (2) : 55-9. J. Orthod. Sci. Meeran N.A. 2 73 2013 10.4103/2278-0203.119678 Meeran NA. Iatrogenic possibilities of orthodontic treatment and modalities of prevention. J Orthod Sci 2013; 2 (3) : 73-86. Semin. Orthod. Krishnan V. 13 257 2007 10.1053/j.sodo.2007.08.007 Krishnan V, Ambili R, Davidovitch Z, Murphy NC. Gingiva and orthodontic treatment. Semin Orthod 2007; 13 : 257-71. Orthod. Craniofac. Res. Ristic M. 10 187 2007 10.1111/j.1601-6343.2007.00396.x Ristic M, Vlahovic Svabic M, Sasic M, Zelic O. Clinical and microbiological effects of fixed orthodontic appliances on periodontal tissues in adolescents. Orthod Craniofac Res 2007; 10 (4) : 187-95. Eur. J. Orthod. Sukontapatipark W. 23 475 2001 10.1093/ejo/23.5.475 Sukontapatipark W, el-Agroudi MA, Selliseth NJ, Thunold K, Selvig KA. Bacterial colonization associated with fixed orthodontic appliances. A scanning electron microscopy study. Eur J Orthod 2001; 23 (5) : 475-84. Am. J. Orthod. Dentofacial Orthop. Davies T.M. 99 155 1991 10.1016/0889-5406(91)70118-G Davies TM, Shaw WC, Worthington HV, Addy M, Dummer P, Kingdon A. The effect of orthodontic treatment on plaque and gingivitis. Am J Orthod Dentofacial Orthop 1991; 99 (2) : 155-61. Am. J. Orthod. Dentofacial Orthop. Thornberg M.J. 135 95 2009 10.1016/j.ajodo.2007.02.057 Thornberg MJ, Riolo CS, Bayirli B, Riolo ML, Van Tubergen EA, Kulbersh R. Periodontal pathogen levels in adolescents before, during, and after fixed orthodontic appliance therapy. Am J Orthod Dentofacial Orthop 2009; 135 (1) : 95-8. J. Periodontol. van Gastel J. 79 2078 2008 10.1902/jop.2008.080153 van Gastel J, Quirynen M, Teughels W, Coucke W, Carels C. Longitudinal changes in microbiology and clinical periodontal variables after placement of fixed orthodontic appliances. J Periodontol 2008; 79 (11) : 2078-86. Am. J. Orthod. Dentofacial Orthop. Paolantonio M. 115 423 1999 10.1016/S0889-5406(99)70263-5 Paolantonio M, Festa F, di Placido G, D’Attilio M, Catamo G, Piccolomini R. Site-specific subgingival colonization by Actinobacillus actinomycetemcomitans in orthodontic patients. Am J Orthod Dentofacial Orthop 1999; 115 (4) : 423-8. Angle Orthod. Kaygisiz E. 85 468 2015 10.2319/041714-289.1 Kaygisiz E, Uzuner FD, Yuksel S, et al. Effects of self-ligating and conventional brackets on halitosis and periodontal conditions. Angle Orthod 2015; 85 (3) : 468-73. Am. J. Orthod. Dentofacial Orthop. Naranjo A.A. 130 275.e17 2006 10.1016/j.ajodo.2005.10.022 Naranjo AA, Triviño ML, Jaramillo A, Betancourth M, Botero JE. Changes in the subgingival microbiota and periodontal parameters before and 3 months after bracket placement. Am J Orthod Dentofacial Orthop 2006; 130 (3) : 275.e17-22. Eur. J. Orthod. van Gastel J. 33 15 2011 10.1093/ejo/cjq032 van Gastel J, Quirynen M, Teughels W, Coucke W, Carels C. Longitudinal changes in microbiology and clinical periodontal parameters after removal of fixed orthodontic appliances. Eur J Orthod 2011; 33 (1) : 15-21. Orthod. Craniofac. Res. Ghijselings E. 17 49 2014 10.1111/ocr.12031 Ghijselings E, Coucke W, Verdonck A, et al. Long-term changes in microbiology and clinical periodontal variables after completion of fixed orthodontic appliances. Orthod Craniofac Res 2014; 17 (1) : 49-59. Angle Orthod. Liu H. 81 609 2011 10.2319/082310-352.1 Liu H, Sun J, Dong Y, et al. Periodontal health and relative quantity of subgingival Porphyromonas gingivalis during orthodontic treatment. Angle Orthod 2011; 81 (4) : 609-15.