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        <full_title>The Open Dentistry Journal</full_title>
        <abbrev_title>TODENTJ</abbrev_title>
        <issn media_type="print">1874-2106</issn>
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          <month>12</month>
          <day>31</day>
          <year>2018</year>
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          <volume>12</volume>
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        <issue>1</issue>
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        <titles>
          <title>Microbial Etiology and Antimicrobial Therapy of Peri-implantitis: A Comprehensive Review</title>
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        <contributors>
          <person_name contributor_role="author" sequence="first">
            <given_name>Muhammad Waqar</given_name>
            <surname>Hussain</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Shahabe Saquib</given_name>
            <surname>Abullais</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Talib Amin</given_name>
            <surname>Naqash</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Mohammad Yunis Saleem</given_name>
            <surname>Bhat</surname>
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        <jats:abstract>
                <jats:sec>
                    <jats:title>Introduction:</jats:title>
                    <jats:p>Implants have turned out to be a well-established therapy in dental practice for the replacement of missing teeth and restoration of function.</jats:p>
                    <jats:p>Peri-implant disease denotes the inflammatory condition of surrounding soft and hard tissues.</jats:p>
                    <jats:p>Two terminologies are covered under the impression of peri-implant pathology; peri-implantitis and mucositis. Peri-implant mucositis is a reversible inflammatory process limited to soft tissues around an implant. Peri-implantitis is an inflammatory condition of hard and soft tissue around the dental implant.</jats:p>
                </jats:sec>
                <jats:sec>
                    <jats:title>Microbial Etiology:</jats:title>
                    <jats:p>Bacterial infections are the most common cause of peri-implantitis. It is a variable poly-microbial infection, although generally dominated by Gram-negative anaerobic bacteria Anti-infective therapy should be included in the treatment regime, while treating the peri-implant disease. Antimicrobial therapy includes local debridement, antibiotic therapy and surface decontamination of the implant.</jats:p>
                </jats:sec>
                <jats:sec>
                    <jats:title>Conclusion:</jats:title>
                    <jats:p>The current article gives a detailed overview of microbial etiology, antimicrobial therapy and its limitations for the treatment of peri-implant Pathology.</jats:p>
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