TODENTJ-25-03-2019_TODENTJ-11-701
1553507241
Bentham Open
doi@benthamopen.net
Bentham Open
The Open Dentistry Journal
TODENTJ
1874-2106
12
29
2017
11
1
Relationship Between Periodontal Disease and Serum Factors in Patients Undergoing Hemodialysis
Narges
Naghsh
Negar Kanuni
Sabet
Forozan
Vahidi
Ahmad
Mogharehabed
Jaber
Yaghini
Background:
Chronic renal disease is a common condition with several recognized risk factors. Periodontal disease is a recently suggested risk factor for renal disease. We aimed to assess the relationship between periodontal disease and several serum factors in patients undergoing hemodialysis.
Methods:
This descriptive cross-sectional study was conducted on 57 patients undergoing hemodialysis. Periodontal examination was done by measuring the mean Pocket Depth (PD), Silness-Löe Plaque Index (PI), Ainamo and Bay Bleeding On Probing (BOP), Löe and Silness Gingival Index (GI) and Clinical Attachment Loss (CAL). Serum levels of albumin, calcium, phosphorus, hemoglobin, ferritin and creatinine were measured via a routine blood test. Cystatin C was separately measured. Data were analyzed using independent t-test, Pearson’s correlation coefficient, chi square test and Mann Whitney test (alpha=0.05).
Results:
37 men and 20 women were evaluated. Of these, 26.3% had periodontitis and 73.7% had gingivitis. Serum level of albumin (P=0.02) and ferritin (P=0.043) in patients with periodontitis was significantly higher than that in patients with gingivitis. The serum level of creatinine (P=0.02), cystatin C (P=0.013), calcium (P=0.046) and phosphorus (P=0.037) had a significant correlation with severity of periodontitis and increase in CAL.
Conclusion:
Increase in the serum levels of albumin and ferritin was related to the progression of gingivitis to periodontitis. Also, the serum levels of creatinine, cystatin C, calcium and phosphorus increased with an increase in CAL.
12
29
2017
701
709
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benthamopen.com
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2017-07-16
2017-10-21
2017-11-27
2017-12-29
https://creativecommons.org/licenses/by/4.0/legalcode
10.2174/1874210601711010701
1553507241
https://opendentistryjournal.com/VOLUME/11/PAGE/701/
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