TODENTJ-25-03-2019_TODENTJ-11-65 1553506959 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 01 31 2017 11 1 Karlsson Lena Kjaeldgaard Marianne Background: Dentin hypersensitivity (DH) is a frequent condition in adults and difficult to treat. The aim of this single-blind, randomised controlled clinical trial was to investigate immediate and long-term effect of ozone treatment (Prozone, W&H NORDIC AB) for 12 seconds on hypersensitive teeth compared to placebo treatment, using a split-mouth design. Methods: 26 patients (12 M, 14 F, mean age 44+ 2) were included in the study having at least two teeth with confirmed DH in different quadrants of the dentition (each subject had one test and one control tooth). A visual analogue scale (VAS) was used to measure the patients´ pain perception immediately and at a long-term follow-up three months later. Results: Significant reduction in pain perception from DH surfaces was demonstrated from ozone treated test teeth as well as in placebo treated control teeth. We found a moderate (16.2%) but significant pain relief (p< 0.012) over time in 57.7% of all treated teeth. Conclusion: Results from this study confirm previously published results showing no significant effect of ozone treatment on hypersensitive teeth compared to placebo treatment. 01 31 2017 65 70 TODENTJ-11-65 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2016-08-16 2016-12-20 2016-12-24 2017-01-31 https://creativecommons.org/licenses/by/4.0/legalcode 10.2174/1874210601711010065 1553506959 https://opendentistryjournal.com/VOLUME/11/PAGE/65/ https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.pdf https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-65/TODENTJ-11-65.xml Gen. 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