<?xml version="1.0"?>
<doi_batch xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.crossref.org/schema/4.4.0" xmlns:fr="http://www.crossref.org/fundref.xsd" xmlns:ct="http://www.crossref.org/clinicaltrials.xsd" xmlns:ai="http://www.crossref.org/AccessIndicators.xsd" xmlns:rel="http://www.crossref.org/relations.xsd" xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1" version="4.4.0" xsi:schemaLocation="http://www.crossref.org/schema/4.4.0 crossref4.4.0.xsd">
  <head>
    <doi_batch_id>TODENTJ-25-03-2019_TODENTJ-11-133</doi_batch_id>
    <timestamp>1553506994</timestamp>
    <depositor>
      <depositor_name>Bentham Open</depositor_name>
      <email_address>doi@benthamopen.net</email_address>
    </depositor>
    <registrant>Bentham Open</registrant>
  </head>
  <body>
    <journal>
      <journal_metadata language="en">
        <full_title>The Open Dentistry Journal</full_title>
        <abbrev_title>TODENTJ</abbrev_title>
        <issn media_type="print">1874-2106</issn>
      </journal_metadata>
      <journal_issue>
        <publication_date media_type="print">
          <month>03</month>
          <day>22</day>
          <year>2017</year>
        </publication_date>
        <journal_volume>
          <volume>11</volume>
        </journal_volume>
        <issue>1</issue>
      </journal_issue>
      <journal_article publication_type="full_text">
        <titles>
          <title>Assessment of the Amount of Calcium Ions Released after the use of Different Chelating Agents and Agitation Protocols</title>
        </titles>
        <contributors>
          <person_name contributor_role="author" sequence="first">
            <given_name>Fábio Luis Miranda</given_name>
            <surname>Pedro</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Laura Maria Amorim Santana</given_name>
            <surname>Costa</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Gilberto Siebert</given_name>
            <surname>Filho</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Orlando Aguirre</given_name>
            <surname>Guedes</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Thiago Machado</given_name>
            <surname>Pereira</surname>
          </person_name>
          <person_name contributor_role="author" sequence="additional">
            <given_name>Alvaro Henrique</given_name>
            <surname>Borges</surname>
          </person_name>
        </contributors>
        <jats:abstract>
                <jats:sec>
                    <jats:title>Background:</jats:title> 
                <jats:p>The main goal of endodontic treatment is to achieve cleaning and shaping prior to the filling process.</jats:p> 
                </jats:sec>
                <jats:sec>
                    <jats:title>Objective:</jats:title> 
                <jats:p>This study aimed to evaluate, using atomic absorption spectrometry, the release of Calcium ions after the use of different chelating agents and protocols of agitation.</jats:p> 
                </jats:sec>
                <jats:sec>
                    <jats:title>Method:</jats:title> 
                <jats:p>Ninety human canine teeth were randomly assigned to one of nine groups (n=10), as follows: 1) 0.2% Chitosan and manual agitation; 2) 0.2% Chitosan and sonic agitation; 3) 0.2% Chitosan and ultrasonic agitation; 4) 17% EDTA and manual agitation; 5) 17% EDTA and sonic agitation; 6) 17% EDTA and ultrasonic agitation; 7) distilled water and manual agitation; 8) distilled water and sonic agitation; 9) distilled water and ultrasonic agitation. Following instrumentation, all chelating substances remained inside the root canal for 3 min. Then the fluid was collected for the identification and quantification of Calcium ions. The amount of Calcium ions released in each group was compared using analysis of variance (ANOVA) and the Kolmogorov-Smirnov and Levene tests followed by Tukey’s post-hoc test. Significance was set at 5%.</jats:p> 
                </jats:sec>
                <jats:sec>
                    <jats:title>Results:</jats:title> 
                <jats:p>The groups in which 0.2% Chitosan was used showed the highest concentration of Calcium ions (p&lt;0.05). Concerning the agitation method, ultrasonic agitation showed the greatest values, followed by sonic and manual agitation (all comparisons, p&lt;0.05).</jats:p> 
                </jats:sec>
                <jats:sec>
                    <jats:title>Conclusion:</jats:title> 
                <jats:p>The present findings suggest that, among the combinations here tested, Chitosan associated with ultrasonic agitation yielded the greatest release of Calcium ions.</jats:p>
                </jats:sec>
            </jats:abstract>
        <publication_date>
          <month>03</month>
          <day>22</day>
          <year>2017</year>
        </publication_date>
        <pages>
          <first_page>133</first_page>
          <last_page>139</last_page>
        </pages>
        <publisher_item>
          <identifier id_type="sici">TODENTJ-11-133</identifier>
        </publisher_item>
        <crossmark>
          <crossmark_version>1</crossmark_version>
          <crossmark_policy>10.2174/crossmark_policy</crossmark_policy>
          <crossmark_domains>
            <crossmark_domain>
              <domain>opendentistryjournal.com</domain>
            </crossmark_domain>
            <crossmark_domain>
              <domain>benthamopen.com</domain>
            </crossmark_domain>
          </crossmark_domains>
          <crossmark_domain_exclusive>true</crossmark_domain_exclusive>
          <custom_metadata>
            <assertion name="review_status" label="Review Status" group_name="peer_review_details" group_label="Peer Review Details" order="0">Peer Reviewed</assertion>
            <assertion name="review_process" label="Review Process" group_name="peer_review_details" group_label="Peer Review Details" order="1">Single blind</assertion>
            <assertion name="screening_status" label="Screening Status" group_name="plagiarism_screening" group_label="Plagiarism Screening" order="0">Checked with iThenticate</assertion>
            <assertion name="received" label="Received" group_name="publication_history" group_label="Publication History" order="0">2016-08-17</assertion>
            <assertion name="revised" label="Revised" group_name="publication_history" group_label="Publication History" order="1">2017-01-09</assertion>
            <assertion name="accepted" label="Accepted" group_name="publication_history" group_label="Publication History" order="2">2017-01-23</assertion>
            <assertion name="published" label="Published" group_name="publication_history" group_label="Publication History" order="3">2017-03-22</assertion>
            <ai:program name="AccessIndicators">
              <ai:license_ref>https://creativecommons.org/licenses/by/4.0/legalcode</ai:license_ref>
            </ai:program>
          </custom_metadata>
        </crossmark>
        <doi_data>
          <doi>10.2174/1874210601711010133</doi>
          <timestamp>1553506994</timestamp>
          <resource>https://opendentistryjournal.com/VOLUME/11/PAGE/133/</resource>
          <collection property="crawler-based">
            <item crawler="google">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item crawler="msn">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item crawler="altavista">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item crawler="yahoo">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item crawler="scirus">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item crawler="iParadigms">
              <resource>https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
          </collection>
          <collection property="text-mining">
            <item>
              <resource mime_type="application/pdf">https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.pdf</resource>
            </item>
            <item>
              <resource mime_type="application/xml">https://opendentistryjournal.com/contents/volumes/V11/TODENTJ-11-133/TODENTJ-11-133.xml</resource>
            </item>
          </collection>
        </doi_data>
        <citation_list>
          <citation key="ref1">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Schäfer E.</author>
            <volume>35</volume>
            <first_page>514</first_page>
            <cYear>2002</cYear>
            <doi>10.1046/j.1365-2591.2002.00515.x</doi>
            <unstructured_citation>
                    Schäfer E, Lohmann D. 
                    Efficiency of rotary nickel-titanium FlexMaster instruments compared with stainless steel hand K-Flexo file Part 2. Cleaning effectiveness and instrumentation results in severely curved root canals of extracted teeth. 
                    Int Endod J  
                    2002; 
                    35
                    (6)
                    : 514-21.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref2">
            <journal_title>J. Endod.</journal_title>
            <author>Khedmat S.</author>
            <volume>34</volume>
            <first_page>599</first_page>
            <cYear>2008</cYear>
            <doi>10.1016/j.joen.2008.02.023</doi>
            <unstructured_citation>
                    Khedmat S, Shokouhinejad N. 
                    Comparison of the efficacy of three chelating agents in smear layer removal. 
                    J Endod  
                    2008; 
                    34
                    (5)
                    : 599-602.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref3">
            <journal_title>Braz. Dent. J.</journal_title>
            <author>Pimenta J.A.</author>
            <volume>23</volume>
            <first_page>212</first_page>
            <cYear>2012</cYear>
            <doi>10.1590/S0103-64402012000300005</doi>
            <unstructured_citation>
                    Pimenta JA, Zaparolli D, Pécora JD, Cruz-Filho AM. 
                    Chitosan: effect of a new chelating agent on the microhardness of root dentin. 
                    Braz Dent J  
                    2012; 
                    23
                    (3)
                    : 212-7.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref4">
            <journal_title>J. Clin. Pediatr. Dent.</journal_title>
            <author>Pintor A.V.</author>
            <volume>40</volume>
            <first_page>1</first_page>
            <cYear>2016</cYear>
            <doi>10.17796/1053-4628-40.1.1</doi>
            <unstructured_citation>
                    Pintor AV, Dos Santos MR, Ferreira DM, Barcelos R, Primo LG, Maia LC. 
                    Does smear layer removal influence root canal therapy outcome? A systematic review. 
                    J Clin Pediatr Dent  
                    2016; 
                    40
                    (1)
                    : 1-7.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref5">
            <journal_title>J. Endod.</journal_title>
            <author>Kokkas A.B.</author>
            <volume>30</volume>
            <first_page>100</first_page>
            <cYear>2004</cYear>
            <doi>10.1097/00004770-200402000-00009</doi>
            <unstructured_citation>
                    Kokkas AB, Boutsioukis ACh, Vassiliadis LP, Stavrianos CK. 
                    The influence of the smear layer on dentinal tubule penetration depth by three different root canal sealers: an in vitro study. 
                    J Endod  
                    2004; 
                    30
                    (2)
                    : 100-2.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref6">
            <journal_title>J. Contemp. Dent. Pract.</journal_title>
            <author>Nischith K.G.</author>
            <volume>13</volume>
            <first_page>23</first_page>
            <cYear>2012</cYear>
            <doi>10.5005/jp-journals-10024-1090</doi>
            <unstructured_citation>
                    Nischith KG, Srikumar GP, Razvi S, Chandra RV. 
                    Effect of smear layer on the apical seal of endodontically treated teeth: An ex vivo study. 
                    J Contemp Dent Pract  
                    2012; 
                    13
                    (1)
                    : 23-6.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref7">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Ruiz-Linares M.</author>
            <volume>50</volume>
            <first_page>77</first_page>
            <cYear>2017</cYear>
            <doi>10.1111/iej.12598</doi>
            <unstructured_citation>
                    Ruiz-Linares M, Aguado-Pérez B, Baca P, Arias-Moliz MT, Ferrer-Luque CM. 
                    Efficacy of antimicrobial solutions against polymicrobial root canal biofilm. 
                    Int Endod J  
                    2017; 
                    50
                    (1)
                    : 77-83.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref8">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Tartari T.</author>
            <volume>50</volume>
            <first_page>106</first_page>
            <cYear>2017</cYear>
            <doi>10.1111/iej.12595</doi>
            <unstructured_citation>
                    Tartari T, Oda DF, Zancan RF, et al. 
                    Mixture of alkaline tetrasodium EDTA with sodium hypochlorite promotes in vitro smear layer removal and organic matter dissolution during biomechanical preparation. 
                    Int Endod J  
                    2017; 
                    50
                    (1)
                    : 106-14.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref9">
            <journal_title>Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.</journal_title>
            <author>Haznedaroğlu F.</author>
            <volume>96</volume>
            <first_page>340</first_page>
            <cYear>2003</cYear>
            <doi>10.1016/S1079-2104(03)00164-1</doi>
            <unstructured_citation>
                    Haznedaroğlu F. 
                    Efficacy of various concentrations of Citric acid at different pH values for smear layer removal. 
                    Oral Surg Oral Med Oral Pathol Oral Radiol Endod  
                    2003; 
                    96
                    (3)
                    : 340-4.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref10">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Violich D.R.</author>
            <volume>43</volume>
            <first_page>2</first_page>
            <cYear>2010</cYear>
            <doi>10.1111/j.1365-2591.2009.01627.x</doi>
            <unstructured_citation>
                    Violich DR, Chandler NP. 
                    The smear layer in endodontics: A review. 
                    Int Endod J  
                    2010; 
                    43
                    (1)
                    : 2-15.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref11">
            <journal_title>J. Endod.</journal_title>
            <author>Cruz-Filho A.M.</author>
            <volume>37</volume>
            <first_page>358</first_page>
            <cYear>2011</cYear>
            <doi>10.1016/j.joen.2010.12.001</doi>
            <unstructured_citation>
                    Cruz-Filho AM, Sousa-Neto MD, Savioli RN, Silva RG, Vansan LP, Pécora JD. 
                    Effect of chelating solutions on the microhardness of root canal lumen dentin. 
                    J Endod  
                    2011; 
                    37
                    (3)
                    : 358-62.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref12">
            <journal_title>J. Endod.</journal_title>
            <author>Spanó J.C.</author>
            <volume>35</volume>
            <first_page>727</first_page>
            <cYear>2009</cYear>
            <doi>10.1016/j.joen.2009.02.008</doi>
            <unstructured_citation>
                    Spanó JC, Silva RG, Guedes DF, Sousa-Neto MD, Estrela C, Pécora JD. 
                    Atomic absorption spectrometry and scanning electron microscopy evaluation of concentration of Calcium ions and smear layer removal with root canal chelators. 
                    J Endod  
                    2009; 
                    35
                    (5)
                    : 727-30.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref13">
            <journal_title>J. Endod.</journal_title>
            <author>Prado M.</author>
            <volume>37</volume>
            <first_page>255</first_page>
            <cYear>2011</cYear>
            <doi>10.1016/j.joen.2010.11.011</doi>
            <unstructured_citation>
                    Prado M, Gusman H, Gomes BP, Simão RA. 
                    Scanning electron microscopic investigation of the effectiveness of Phosphoric acid in smear layer removal when compared with EDTA and Citric acid. 
                    J Endod  
                    2011; 
                    37
                    (2)
                    : 255-8.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref14">
            <journal_title>Mar. Biotechnol.</journal_title>
            <author>Kurita K.</author>
            <volume>8</volume>
            <first_page>203</first_page>
            <cYear>2006</cYear>
            <doi>10.1007/s10126-005-0097-5</doi>
            <unstructured_citation>
                    Kurita K. 
                    Chitin and Chitosan: functional biopolymers from marine crustaceans. 
                    Mar Biotechnol  
                    2006; 
                    8
                    (3)
                    : 203-26.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref15">
            <journal_title>J. Clin. Periodontol.</journal_title>
            <author>Park J.S.</author>
            <volume>30</volume>
            <first_page>443</first_page>
            <cYear>2003</cYear>
            <doi>10.1034/j.1600-051X.2003.10283.x</doi>
            <unstructured_citation>
                    Park JS, Choi SH, Moon IS, Cho KS, Chai JK, Kim CK. 
                    Eight-week histological analysis on the effect of Chitosan on surgically created one-wall intrabony defects in beagle dogs. 
                    J Clin Periodontol  
                    2003; 
                    30
                    (5)
                    : 443-53.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref16">
            <journal_title>J. Endod.</journal_title>
            <author>Ballal N.V.</author>
            <volume>36</volume>
            <first_page>862</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2009.12.021</doi>
            <unstructured_citation>
                    Ballal NV, Shavi GV, Kumar R, Kundabala M, Bhat KS. 
                    
                        In vitro sustained release of Calcium ions and pH maintenance from different vehicles containing Calcium hydroxide. 
                    J Endod  
                    2010; 
                    36
                    (5)
                    : 862-6.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref17">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Teixeira C.S.</author>
            <volume>38</volume>
            <first_page>285</first_page>
            <cYear>2005</cYear>
            <doi>10.1111/j.1365-2591.2005.00930.x</doi>
            <unstructured_citation>
                    Teixeira CS, Felippe MC, Felippe WT. 
                    The effect of application time of EDTA and NaOCl on intracanal smear layer removal: an SEM analysis. 
                    Int Endod J  
                    2005; 
                    38
                    (5)
                    : 285-90.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref18">
            <journal_title>J. Endod.</journal_title>
            <author>Klyn S.L.</author>
            <volume>36</volume>
            <first_page>1367</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2010.03.022</doi>
            <unstructured_citation>
                    Klyn SL, Kirkpatrick TC, Rutledge RE. 
                    
                        In vitro comparisons of debris removal of the EndoActivator system, the F file, ultrasonic irrigation, and NaOCl irrigation alone after hand-rotary instrumentation in human mandibular molars. 
                    J Endod  
                    2010; 
                    36
                    (8)
                    : 1367-71.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref19">
            <journal_title>J. Endod.</journal_title>
            <author>Paragliola R.</author>
            <volume>36</volume>
            <first_page>282</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2009.10.004</doi>
            <unstructured_citation>
                    Paragliola R, Franco V, Fabiani C, et al. 
                    Final rinse optimization: influence of different agitation protocols. 
                    J Endod  
                    2010; 
                    36
                    (2)
                    : 282-5.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref20">
            <journal_title>Oral Surg. Oral Med. Oral Pathol.</journal_title>
            <author>Schneider S.W.</author>
            <volume>32</volume>
            <first_page>271</first_page>
            <cYear>1971</cYear>
            <doi>10.1016/0030-4220(71)90230-1</doi>
            <unstructured_citation>
                    Schneider SW. 
                    A comparison of canal preparations in straight and curved root canals. 
                    Oral Surg Oral Med Oral Pathol  
                    1971; 
                    32
                    (2)
                    : 271-5.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref21">
            <journal_title>J. Endod.</journal_title>
            <author>Myers G.L.</author>
            <volume>17</volume>
            <first_page>275</first_page>
            <cYear>1991</cYear>
            <doi>10.1016/S0099-2399(06)81866-2</doi>
            <unstructured_citation>
                    Myers GL, Montgomery S. 
                    A comparison of weights of debris extruded apically by conventional filing and Canal Master techniques. 
                    J Endod  
                    1991; 
                    17
                    (6)
                    : 275-9.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref22">
            <journal_title>J. Mater. Sci. Mater. Med.</journal_title>
            <author>Wu Y.</author>
            <volume>19</volume>
            <first_page>3621</first_page>
            <cYear>2008</cYear>
            <doi>10.1007/s10856-008-3477-3</doi>
            <unstructured_citation>
                    Wu Y, Hu Y, Cai J, Ma S, Wang X. 
                    Coagulation property of Hyaluronic acid-collagen/Chitosan complex film. 
                    J Mater Sci Mater Med  
                    2008; 
                    19
                    (12)
                    : 3621-9.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref23">
            <journal_title>J. Endod.</journal_title>
            <author>Shahravan A.</author>
            <volume>33</volume>
            <first_page>96</first_page>
            <cYear>2007</cYear>
            <doi>10.1016/j.joen.2006.10.007</doi>
            <unstructured_citation>
                    Shahravan A, Haghdoost AA, Adl A, Rahimi H, Shadifar F. 
                    Effect of smear layer on sealing ability of canal obturation: A systematic review and meta-analysis. 
                    J Endod  
                    2007; 
                    33
                    (2)
                    : 96-105.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref24">
            <journal_title>Braz. Dent. J.</journal_title>
            <author>Silva P.V.</author>
            <volume>23</volume>
            <first_page>357</first_page>
            <cYear>2012</cYear>
            <doi>10.1590/S0103-64402012000400008</doi>
            <unstructured_citation>
                    Silva PV, Guedes DF, Pécora JD, da Cruz-Filho AM. 
                    Time-dependent effects of Chitosan on dentin structures. 
                    Braz Dent J  
                    2012; 
                    23
                    (4)
                    : 357-61.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref25">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Silva P.V.</author>
            <volume>46</volume>
            <first_page>332</first_page>
            <cYear>2013</cYear>
            <doi>10.1111/j.1365-2591.2012.02119.x</doi>
            <unstructured_citation>
                    Silva PV, Guedes DF, Nakadi FV, Pécora JD, Cruz-Filho AM. 
                    Chitosan: A new solution for removal of smear layer after root canal instrumentation. 
                    Int Endod J  
                    2013; 
                    46
                    (4)
                    : 332-8.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref26">
            <journal_title>Int. Endod. J.</journal_title>
            <author>Machado-Silveiro L.F.</author>
            <volume>37</volume>
            <first_page>365</first_page>
            <cYear>2004</cYear>
            <doi>10.1111/j.1365-2591.2004.00813.x</doi>
            <unstructured_citation>
                    Machado-Silveiro LF, González-López S, González-Rodríguez MP. 
                    Decalcification of root canal dentine by Citric acid, EDTA and Sodium citrate. 
                    Int Endod J  
                    2004; 
                    37
                    (6)
                    : 365-9.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref27">
            <journal_title>Polym. Degrad. Stabil.</journal_title>
            <author>Kurita K.</author>
            <volume>59</volume>
            <first_page>117</first_page>
            <cYear>1998</cYear>
            <doi>10.1016/S0141-3910(97)00160-2</doi>
            <unstructured_citation>
                    Kurita K. 
                    Chemistry and application of chitin and Chitosan. 
                    Polym Degrad Stabil  
                    1998; 
                    59
                    (1-3)
                    : 117-20.
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref28">
            <journal_title>Restor. Dent. Endod</journal_title>
            <author>Del Carpio-Perochena A.</author>
            <volume>40</volume>
            <first_page>195</first_page>
            <cYear>2015</cYear>
            <doi>10.5395/rde.2015.40.3.195</doi>
            <unstructured_citation>
                    Del Carpio-Perochena A, Bramante CM, Duarte MA, de Moura MR, Aouada FA, Kishen A. 
                    Chelating and antibacterial properties of Chitosan nanoparticles on dentin. 
                    Restor Dent Endod  
                    2015; 
                    40
                    (3)
                    : 195-201.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref29">
            <journal_title>J. Biomed. Mater. Res. B Appl. Biomater.</journal_title>
            <author>Xu Z.</author>
            <volume>98</volume>
            <first_page>150</first_page>
            <cYear>2011</cYear>
            <doi>10.1002/jbm.b.31844</doi>
            <unstructured_citation>
                    Xu Z, Neoh KG, Lin CC, Kishen A. 
                    Biomimetic deposition of Calcium phosphate minerals on the surface of partially demineralized dentine modified with phosphorylated Chitosan. 
                    J Biomed Mater Res B Appl Biomater  
                    2011; 
                    98
                    (1)
                    : 150-9.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref30">
            <journal_title>J. Endod.</journal_title>
            <author>Rödig T.</author>
            <volume>36</volume>
            <first_page>1983</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2010.08.056</doi>
            <unstructured_citation>
                    Rödig T, Döllmann S, Konietschke F, Drebenstedt S, Hülsmann M. 
                    Effectiveness of different irrigant agitation techniques on debris and smear layer removal in curved root canals: A scanning electron microscopy study. 
                    J Endod  
                    2010; 
                    36
                    (12)
                    : 1983-7.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref31">
            <journal_title>Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.</journal_title>
            <author>Kanter V.</author>
            <volume>112</volume>
            <first_page>809</first_page>
            <cYear>2011</cYear>
            <doi>10.1016/j.tripleo.2011.06.002</doi>
            <unstructured_citation>
                    Kanter V, Weldon E, Nair U, et al. 
                    A quantitative and qualitative analysis of ultrasonic vs. sonic endodontic systems on canal cleanliness and obturation. 
                    Oral Surg Oral Med Oral Pathol Oral Radiol Endod  
                    2011; 
                    112
                    (6)
                    : 809-13.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref32">
            <journal_title>J. Endod.</journal_title>
            <author>Klyn S.L.</author>
            <volume>36</volume>
            <first_page>1367</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2010.03.022</doi>
            <unstructured_citation>
                    Klyn SL, Kirkpatrick TC, Rutledge RE. 
                    
                        In vitro comparisons of debris removal of the Endo Activator system, the F file, ultrasonic irrigation, and NaOCl irrigation alone after hand-rotary instrumentation in human mandibular molars. 
                    J Endod  
                    2010; 
                    36
                    (8)
                    : 1367-71.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref33">
            <journal_title>J. Endod.</journal_title>
            <author>Jiang L.M.</author>
            <volume>36</volume>
            <first_page>143</first_page>
            <cYear>2010</cYear>
            <doi>10.1016/j.joen.2009.06.009</doi>
            <unstructured_citation>
                    Jiang LM, Verhaagen B, Versluis M, van der Sluis LW. 
                    Evaluation of a sonic device designed to activate irrigant in the root canal. 
                    J Endod  
                    2010; 
                    36
                    (1)
                    : 143-6.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref34">
            <journal_title>J. Endod.</journal_title>
            <author>Lui J.N.</author>
            <volume>33</volume>
            <first_page>472</first_page>
            <cYear>2007</cYear>
            <doi>10.1016/j.joen.2006.12.007</doi>
            <unstructured_citation>
                    Lui JN, Kuah HG, Chen NN. 
                    Effect of EDTA with and without surfactants or ultrasonics on removal of smear layer. 
                    J Endod  
                    2007; 
                    33
                    (4)
                    : 472-5.
                    
                    
                    
                </unstructured_citation>
          </citation>
          <citation key="ref35">
            <journal_title>Iran. Endod. J.</journal_title>
            <author>Mohammadi Z.</author>
            <volume>10</volume>
            <first_page>216</first_page>
            <cYear>2015</cYear>
            <unstructured_citation>
                    Mohammadi Z, Shalavi S, Giardino L, Palazzi F, Asgary S. 
                    Impact of ultrasonic activation on the effectiveness of Sodium hypochlorite: A review. 
                    Iran Endod J  
                    2015; 
                    10
                    (4)
                    : 216-20.
                    
                    
                </unstructured_citation>
          </citation>
        </citation_list>
      </journal_article>
    </journal>
  </body>
</doi_batch>
