TODENTJ-25-03-2019_TODENTJ-10-395 1553506544 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 08 22 2016 10 1 Carlo Maiorana Mario Beretta Luca Pivetti Enrico Stoffella Giovanni B. Grossi Alan S. Herford Background: The presence of keratinized tissue around dental implants is more than desirable either from a functional and aesthetic point of view, making soft tissue grafting a common practice in implant rehabilitation. Autogenous soft tissue grafting procedures are usually associated with high morbidity. Aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants. Methods: 15 consecutive patients underwent a vestibuloplasty and grafting, both in the mandible and the maxilla, with a collagen matrix. Results: The primary endpoint was to evaluate the resorption of the graft along with the re-epithelization grafted area. The percentage of the resorption was 44,4%, with a mean gain in vestibular height of 3 mm. Secondary endpoints evaluated the clinical appearance, the hemostatic effect and the post-operative pain. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection were noted. Conclusion: This study showed that the used collagen matrix can find major interest in those patients who need a greater aesthetic outcome as the matrix has a perfect integration with the surrounding tissues. Furthermore it is strongly recommended for those patients who can bear little pain. Clinical Significance: Post-operative morbidity of autologous grafts is the biggest concern of this type of surgery. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery. The present study showed the efficacy of a collagen matrix as this kind of substitute. 08 22 2016 395 410 TODENTJ-10-395 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2014-12-24 2016-05-24 2016-07-13 2016-08-22 https://creativecommons.org/licenses/by/4.0/legalcode 10.2174/1874210601610010395 1553506544 https://opendentistryjournal.com/VOLUME/10/PAGE/395/ https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-395/TODENTJ-10-395.xml J. 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