TODENTJ-25-03-2019_TODENTJ-10-375 1553506539 Bentham Open doi@benthamopen.net Bentham Open The Open Dentistry Journal TODENTJ 1874-2106 08 12 2016 10 1 Moritz Hertel Katja Sommer Eckehard Kostka Sandra Maria Imiolczyk Husam Ballout Saskia Preissner The aim of the present study was to investigate the clinical outcomes of two different standardized endodontic irrigation protocols. It was assumed that the additional use of ethylenediaminetetraacetate (EDTA) and passive ultrasonic irrigation (PUI) would result in an increased rate of absence of symptoms and remission based on the periapical index (PAI) compared to passive irrigation using only sodium hypochlorite (NaOCl). Data and radiographs from 199 teeth retrieved from the institutional endodontic database were analyzed retrospectively. In 106 teeth irrigation was performed using only NaOCl (protocol 1). Ninety-three teeth were irrigated using NaOCl and EDTA (protocol 2). Chlorhexidine (CHX) was additionally used in revision treatments in both groups. All irrigants in group 2 were activated by PUI. Mean follow-up periods were: protocol 1 = 9.2 ± 4.4 and protocol 2 = 6.6 ± 2.5 months (p < 0.0001 (chi-square test). The frequencies of the PAImasterpoint and PAIfollow-up scores did not differ significantly between teeth, which received either protocol 1 or 2 (p = 0.555 and 0.138). Statistical analysis revealed no significant association between treatment success (absence of clinical symptoms and PAIfollow-up = I or PAImasterpoint > PAIfollow-up > I) and the applied protocol (success rates: protocol 1 = 72.6% vs. protocol 2 = 82.8%; p = 0.203). Furthermore, the frequency of extractions did not differ significantly between the two protocols (p = 0.102). No association was found between follow-up time and treatment success (p = 0.888). The hypothesis was not confirmed. Even though the obtained success rate was higher after supplementing the irrigation protocol with EDTA and PUI, no significance was recorded. Hence, protocol 2 was not superior to protocol 1 regarding therapy success, at least within the limited follow-up period. It may be cautiously concluded that sufficient mechanical debridement combined with passive NaOCl irrigation results in comparably high success rates compared to EDTA and PUI. 08 12 2016 375 381 TODENTJ-10-375 1 10.2174/crossmark_policy opendentistryjournal.com benthamopen.com true Peer Reviewed Single blind Checked with iThenticate 2016-2-13 2016-5-13 2016-6-24 2016-08-12 https://creativecommons.org/licenses/by-nc/4.0/legalcode 10.2174/1874210616021001375 1553506539 https://opendentistryjournal.com/VOLUME/10/PAGE/375/ https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.pdf https://opendentistryjournal.com/contents/volumes/V10/TODENTJ-10-375/TODENTJ-10-375.xml J. 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