TODENTJ-25-03-2019_TODENTJ-10-330
1553506525
Bentham Open
doi@benthamopen.net
Bentham Open
The Open Dentistry Journal
TODENTJ
1874-2106
06
25
2016
10
1
Diagnosis and Intralesional Corticotherapy in Oral Ulcers Occurring as the Sole Manifestation of Langerhans Cell Histiocytosis. A Case Report
Liane
Gambirazi
Tatiana
Libório
Fábio
Nunes
Norberto
Sugaya
Dante
Migliari
This article reports a case of oral mucosa lesions as the sole manifestation in Langerhans cell histiocytosis (LCH). This is a very uncommon manifestation of LCH since this disease preferably affects the bones with frequent involvement of the jaws. LCH may also involve other organs, particularly the lungs, liver, lymph nodes, and skin. The highlights of this report are the differential diagnosis, immunohistochemical analysis and, mostly, the therapeutic approach.
06
25
2016
330
337
TODENTJ-10-330
1
10.2174/crossmark_policy
opendentistryjournal.com
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2015-12-31
2016-05-04
2016-05-09
2016-06-25
https://creativecommons.org/licenses/by/4.0/legalcode
10.2174/1874210601610010330
1553506525
https://opendentistryjournal.com/VOLUME/10/PAGE/330/
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Lancet
1
208
1987
Histiocytosis syndromes in children. Writing Group of the Histiocyte Society.
Lancet
1987;
1
(8526)
: 208-9.
Lancet
Leonidas J.C.
361
1293
2003
10.1016/S0140-6736(03)12990-X
Leonidas JC, Guelfguat M, Valderrama E.
Langerhans’ cell histiocytosis.
Lancet
2003;
361
(9365)
: 1293-5.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol.
Lee S-H.
116
e255
2013
10.1016/j.oooo.2011.11.035
Lee S-H, Yoon H-J.
Intralesional infiltration of corticosteroids in the treatment of localized Langerhans cell histiocytosis of the mandible: report of two cases.
Oral Surg Oral Med Oral Pathol Oral Radiol
2013;
116
(4)
: e255-60.
Oral Oncol.
Eckardt A.
39
687
2003
10.1016/S1368-8375(03)00080-0
Eckardt A, Schultze A.
Maxillofacial manifestations of Langerhans cell histiocytosis: a clinical and therapeutic analysis of 10 patients.
Oral Oncol
2003;
39
(7)
: 687-94.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
Hicks J.
100
S42
2005
10.1016/j.tripleo.2005.06.016
Hicks J, Flaitz CM.
Langerhans cell histiocytosis: current insights in a molecular age with emphasis on clinical oral and maxillofacial pathology practice.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
2005;
100
(2 Suppl)
: S42-66.
Oral Surg. Oral Med. Oral Pathol.
Bottomley W.K.
63
228
1987
10.1016/0030-4220(87)90318-5
Bottomley WK, Gabriel SA, Corio RL, Jacobson RJ, Rothchild N.
Histiocytosis X: report of an oral soft tissue lesion without bony involvement.
Oral Surg Oral Med Oral Pathol
1987;
63
(2)
: 228-31.
J. Periodontol.
Finney D.S.
59
457
1988
10.1902/jop.1988.59.7.457
Finney DS, Rees TD, Wright JM, Blanton PL.
Solitary eosinophilic granuloma (histiocytosis X) of the gingiva. A report of two cases.
J Periodontol
1988;
59
(7)
: 457-60.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
Cleveland D.B.
82
541
1996
10.1016/S1079-2104(96)80201-0
Cleveland DB, Goldberg KM, Greenspan JS, Seitz TE, Miller AS.
Langerhans’ cell histiocytosis: report of three cases with unusual oral soft tissue involvement.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
1996;
82
(5)
: 541-8.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
Milián M.A.
91
76
2001
10.1067/moe.2001.110031
Milián MA, Bagán JV, Jiménez Y, Pérez A, Scully C, Antoniades D.
Langerhans’ cell histiocytosis restricted to the oral mucosa.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
2001;
91
(1)
: 76-9.
J. Oral Maxillofac. Surg.
Takahashi K.
61
118
2003
10.1053/joms.2003.50019
Takahashi K, Harada M, Kimoto M, Kondo F.
Diagnostic confirmation of Langerhans cell histiocytosis of the jaws with CD1a immunostaining: a case report.
J Oral Maxillofac Surg
2003;
61
(1)
: 118-22.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
Esen A.
109
e53
2010
10.1016/j.tripleo.2009.10.015
Esen A, Dolanmaz D, Kalaycı A, Günhan O, Avunduk MC.
Treatment of localized Langerhans’ cell histiocytosis of the mandible with intralesional steroid injection: report of a case.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
2010;
109
(2)
: e53-8.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol.
Plona G.A.
2015
10.1016/j.oooo.2015.11.008
Plona GA, Wiltz M, Kelsch R.
Spontaneous resolution of an eosinophilic granuloma of the mandible following open biopsy.
Oral Surg Oral Med Oral Pathol Oral Radiol
2015.
pii: S2212-4403(15)01324-3.